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cyclotheonamide A

Names

[ CAS No. ]:
129033-04-1

[ Name ]:
cyclotheonamide A

[Synonym ]:
Cyclotheonamide A

Biological Activity

[Description]:

Cyclotheonamide A is a serine protease inhibitor (cyclic polypeptide), which can be obtained from marine sponges of the genus Theonella. Cyclotheonamide A shows potent inhibitory activity against trypsin (Ki=0.023 µM) and streptokinase (Ki=0.035 µM) and moderate inhibitory activity against human α-thrombin (Ki=0.18 µM). Cyclotheonamide A can be used in study of antithrombotic[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Ser/Thr Protease
Research Areas >> Cardiovascular Disease

Chemical & Physical Properties

[ Density]:
1.44g/cm3

[ Molecular Formula ]:
C36H45N9O8

[ Molecular Weight ]:
731.79800

[ Exact Mass ]:
731.33900

[ PSA ]:
322.29000

[ LogP ]:
3.00970

[ Index of Refraction ]:
1.677

Related Compounds

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