129033-04-1

129033-04-1 structure

Name: cyclotheonamide A
Chemical Name: N-[(1S)-1-amino-3-[(2S)-2-[(E,6S)-6-amino-2-[(4R)-4-amino-2-(4-hydroxyphenyl)-3-oxo-5-phenylpentanimidoyl]-9-(diaminomethylideneamino)-3-formyl-4,5-dioxonon-2-enoyl]pyrrolidin-1-yl]-3-oxopropyl]formamide
CAS Number: 129033-04-1
Molecular Formula: C₃₆H₄₅N₉O₈
Molecular Weight: 731.79800
Catalog: Signaling Pathways Metabolic Enzyme/Protease Ser/Thr Protease
Create Date: 2016-05-11 02:25:37
Modify Date: 2024-01-09 13:32:02
Cyclotheonamide A is a serine protease inhibitor (cyclic polypeptide), which can be obtained from marine sponges of the genus Theonella. Cyclotheonamide A shows potent inhibitory activity against trypsin (Ki=0.023 µM) and streptokinase (Ki=0.035 µM) and moderate inhibitory activity against human α-thrombin (Ki=0.18 µM). Cyclotheonamide A can be used in study of antithrombotic[1].

Name	N-[(1S)-1-amino-3-[(2S)-2-[(E,6S)-6-amino-2-[(4R)-4-amino-2-(4-hydroxyphenyl)-3-oxo-5-phenylpentanimidoyl]-9-(diaminomethylideneamino)-3-formyl-4,5-dioxonon-2-enoyl]pyrrolidin-1-yl]-3-oxopropyl]formamide
Synonyms	Cyclotheonamide A

Description	Cyclotheonamide A is a serine protease inhibitor (cyclic polypeptide), which can be obtained from marine sponges of the genus Theonella. Cyclotheonamide A shows potent inhibitory activity against trypsin (Ki=0.023 µM) and streptokinase (Ki=0.035 µM) and moderate inhibitory activity against human α-thrombin (Ki=0.18 µM). Cyclotheonamide A can be used in study of antithrombotic[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Ser/Thr Protease Research Areas >> Cardiovascular Disease