Tolytoxin

Modify Date: 2025-09-12 18:43:26

Tolytoxin structure	Common Name	Tolytoxin
	CAS Number	127999-44-4	Molecular Weight	850.09
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₆H₇₅NO₁₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Tolytoxin

Tolytoxin, a bioactive metabolite from cyanobacteria, is a potent antifungal antibiotic, exhibiting MICs of 0.25-8 nmol. Tolytoxin is a cyanobacterial macrolide that targets actin by inhibition of its polymerization. Tolytoxin has cytotoxic effects in cancer cells[1].

Name	Tolytoxin

Description	Tolytoxin, a bioactive metabolite from cyanobacteria, is a potent antifungal antibiotic, exhibiting MICs of 0.25-8 nmol. Tolytoxin is a cyanobacterial macrolide that targets actin by inhibition of its polymerization. Tolytoxin has cytotoxic effects in cancer cells[1].
Related Catalog	Research Areas >> Cancer Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal Signaling Pathways >> Antibody-drug Conjugate >> ADC Cytotoxin
In Vivo	Tolytoxin is highly toxic to mice, exhibiting an LD50 (ip) of 1.5 mg/kg.
References	[1]. G M Patterson, et al. Biological effects of tolytoxin (6-hydroxy-7-O-methyl-scytophycin b), a potent bioactive metabolite from cyanobacteria. Arch Microbiol. 1992;157(5):406-10. [2]. Aysegul Dilsizoglu Senol, et al. Effect of tolytoxin on tunneling nanotube formation and function. Sci Rep. 2019 Apr 5;9(1):5741.

Molecular Formula	C₄₆H₇₅NO₁₃
Molecular Weight	850.09
InChIKey	FTGOWEQDZZMPNJ-GUMZKTDUSA-N
SMILES	COC1CC2C=CCC(CC(OC)C3(CO3)C(OC)CC(OC)C(C)C(C(C)C(O)C(C)CCC(=O)C(C)C(OC)C(C)C=CN(C)C=O)OC(=O)C=CC(C)=CC1O)O2

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Tolytoxin
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Tolytoxin
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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Tolytoxin

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