PX20606 trans racemate

Modify Date: 2025-08-25 03:36:08

PX20606 trans racemate Structure
PX20606 trans racemate structure
 Common Name PX20606 trans racemate
CAS Number 1268244-85-4 Molecular Weight 554.85
Density N/A Boiling Point N/A
Molecular Formula C29H22Cl3NO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PX20606 trans racemate


PX20606 trans racemate is a FXR agonist with EC50s of 32 and 34 nM for FXR in FRET and M1H assay, respectively.

 Names

Name 378SU5NO8S
Synonym More Synonyms

 PX20606 trans racemate Biological Activity

Description PX20606 trans racemate is a FXR agonist with EC50s of 32 and 34 nM for FXR in FRET and M1H assay, respectively.
Related Catalog
Target

EC50: 32 nM (FXR in FRET assay), 34 nM (FXR in M1H assay)[1]

References

[1]. Kinzel O, et al. Novel substituted isoxazole FXR agonists with cyclopropyl, hydroxycyclobutyl and hydroxyazetidinyl linkers: Understanding and improving key determinants of pharmacological properties. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3746-53.

 Chemical & Physical Properties

Molecular Formula C29H22Cl3NO4
Molecular Weight 554.85
Storage condition 2-8℃

 Synonyms

6TU6SUZ3BY
UNII:6TU6SUZ3BY
UNII:378SU5NO8S
Benzoic acid, 4-[(1S,2S)-2-[2-chloro-4-[[5-cyclopropyl-3-(2,6-dichlorophenyl)-4-isoxazolyl]methoxy]phenyl]cyclopropyl]-
4-[(1S,2S)-2-(2-Chloro-4-{[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}phenyl)cyclopropyl]benzoic acid
378SU5NO8S
PX20606 trans racemate
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