4-Azido-2,3,5,6-tetrafluorobenzoicacid
Modify Date: 2024-01-09 18:06:47
4-Azido-2,3,5,6-tetrafluorobenzoicacid structure
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Common Name | 4-Azido-2,3,5,6-tetrafluorobenzoicacid | ||
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| CAS Number | 126695-58-7 | Molecular Weight | 332.16700 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C11H4F4N4O4 | Melting Point | 104-105ºC | |
| MSDS | N/A | Flash Point | N/A | |
Use of 4-Azido-2,3,5,6-tetrafluorobenzoicacid4-N3Pfp-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
| Name | N-Succinimidyl 4-Azido-2,3,5,6-tetrafluorobenzoate |
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| Synonym | More Synonyms |
| Description | 4-N3Pfp-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. |
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| Related Catalog | |
| Target |
Noncleavable |
| Melting Point | 104-105ºC |
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| Molecular Formula | C11H4F4N4O4 |
| Molecular Weight | 332.16700 |
| Exact Mass | 332.01700 |
| PSA | 113.43000 |
| LogP | 1.79626 |
| Storage condition | Amber Vial, -20°C Freezer, Under Inert Atmosphere |
| Stability | Light and Moisture Sensitive. Store in freezer |
| Hazard Codes | F+ |
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| RIDADR | UN 1325 4.1/PG III |
| Packaging Group | III |
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~%
4-Azido-2,3,5,6... CAS#:126695-58-7 |
| Literature: Journal of Organic Chemistry, , vol. 55, # 11 p. 3640 - 3647 |
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~%
4-Azido-2,3,5,6... CAS#:126695-58-7 |
| Literature: Journal of Organic Chemistry, , vol. 55, # 11 p. 3640 - 3647 |
|
~%
4-Azido-2,3,5,6... CAS#:126695-58-7 |
| Literature: Journal of Physical Chemistry, , vol. 98, # 2 p. 412 - 419 |
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~98%
4-Azido-2,3,5,6... CAS#:126695-58-7 |
| Literature: Marcinek, Andrzej; Platz, Matthew S.; Chan, Stephen Y.; Floresca, Rey; Rajagopalan, Krishnan; et al. Journal of Physical Chemistry, 1994 , vol. 98, # 2 p. 412 - 419 |
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~95%
4-Azido-2,3,5,6... CAS#:126695-58-7 |
| Literature: THE STATE OF OREGON ACTING BY AND THROUGH STATE BOARD OF HIGHER EDUCATION ON BEHALF OF PORTLAND Patent: US2010/28559 A1, 2010 ; |
|
~%
4-Azido-2,3,5,6... CAS#:126695-58-7 |
| Literature: Journal of Physical Chemistry, , vol. 98, # 2 p. 412 - 419 |
|
~%
4-Azido-2,3,5,6... CAS#:126695-58-7 |
| Literature: Journal of Organic Chemistry, , vol. 55, # 11 p. 3640 - 3647 |
|
~%
4-Azido-2,3,5,6... CAS#:126695-58-7 |
| Literature: Journal of Organic Chemistry, , vol. 55, # 11 p. 3640 - 3647 |
|
~%
4-Azido-2,3,5,6... CAS#:126695-58-7 |
| Literature: Journal of Organic Chemistry, , vol. 55, # 11 p. 3640 - 3647 |
| Precursor 9 | |
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| DownStream 1 | |
CAS#:473721-57-2| 4-Azido-2,3,5,6-tetrafluorobenzoic Acid N-Succinimidyl Ester |
| (2,5-dioxopyrrolidin-1-yl) 4-azido-2,3,5,6-tetrafluorobenzoate |
| ATFB,SE [4-Azido-2,3,5,6-tetrafluorobenzoic acid,succinimidyl ester] |