OTs-C6-OBn
OTs-C6-OBn structure
|
Common Name | OTs-C6-OBn | ||
|---|---|---|---|---|
| CAS Number | 126519-80-0 | Molecular Weight | 380.49800 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H26O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of OTs-C6-OBnOTs-C6-OBn is a PROTAC linker, which refers to the alkyl chain composition. OTs-C6-OBn can be used in the synthesis of PROTAC SGK3 degrader-1 (HY-125878)[1]. |
| Name | 4-methylbenzenesulfonic acid,6-phenylmethoxyhexan-1-ol |
|---|---|
| Synonym | More Synonyms |
| Description | OTs-C6-OBn is a PROTAC linker, which refers to the alkyl chain composition. OTs-C6-OBn can be used in the synthesis of PROTAC SGK3 degrader-1 (HY-125878)[1]. |
|---|---|
| Related Catalog | |
| Target |
Alkyl-Chain |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
| References |
| Molecular Formula | C20H26O4S |
|---|---|
| Molecular Weight | 380.49800 |
| Exact Mass | 380.16600 |
| PSA | 92.21000 |
| LogP | 5.07840 |
| Hazard Codes | Xi |
|---|
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~82%
OTs-C6-OBn CAS#:126519-80-0 |
| Literature: Liu, Peng; Xu, Xing; Chen, Lili; Ma, Lei; Shen, Xu; Hu, Lihong Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 5 p. 1596 - 1607 |
|
~97%
OTs-C6-OBn CAS#:126519-80-0 |
| Literature: Colera, Manuel; Costero, Ana M.; Gavina, Pablo; Gil, Salvador Tetrahedron Asymmetry, 2005 , vol. 16, # 15 p. 2673 - 2679 |
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~%
OTs-C6-OBn CAS#:126519-80-0 |
| Literature: Mori, Kenji; Qian, Zhao-Hui Liebigs Annalen der Chemie, 1994 , # 3 p. 291 - 296 |
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~%
OTs-C6-OBn CAS#:126519-80-0 |
| Literature: Matsumoto, Kazutsugu; Shimojo, Megumi; Hatanaka, Minoru Chemistry Letters, 1997 , # 11 p. 1151 - 1152 |
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~%
OTs-C6-OBn CAS#:126519-80-0 |
| Literature: Shikichi, Yasumasa; Mori, Kenji Bioscience, Biotechnology and Biochemistry, 2012 , vol. 76, # 10 p. 1943 - 1951 |
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~%
OTs-C6-OBn CAS#:126519-80-0 |
| Literature: Liu, Peng; Xu, Xing; Chen, Lili; Ma, Lei; Shen, Xu; Hu, Lihong Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 5 p. 1596 - 1607 |
|
~%
OTs-C6-OBn CAS#:126519-80-0 |
| Literature: Liu, Peng; Xu, Xing; Chen, Lili; Ma, Lei; Shen, Xu; Hu, Lihong Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 5 p. 1596 - 1607 |
| Precursor 8 | |
|---|---|
| DownStream 5 | |
CAS#:54247-27-7
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CAS#:61103-84-2| 6-benzyloxy-1-hexyl 4-toluenesulfonate |
| 6-benzyloxyhexyl tosylate |
| 6-benzyloxyhexyl 4-methylbenzenesulfonate |