OVA Peptide (257-264) TFA
Modify Date: 2025-08-24 19:14:31
OVA Peptide (257-264) TFA structure
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Common Name | OVA Peptide (257-264) TFA | ||
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| CAS Number | 1262751-08-5 | Molecular Weight | 1077.15 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C47H75F3N10O15 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of OVA Peptide (257-264) TFAOVA Peptide (257-264) TFA is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide from ovalbumin presented by the class I MHC molecule, H-2Kb. |
| Name | OVA Peptide (257-264) TFA |
|---|
| Description | OVA Peptide (257-264) TFA is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide from ovalbumin presented by the class I MHC molecule, H-2Kb. |
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| Related Catalog | |
| In Vitro | TAP1-I- and C57BL/6 macrophages may process Crl-OVA and full-length OVA in different cellular compartments and that the protein context of the OVA Peptide (257-264) epitope influences the extent of TAP-independent processing for MHC class I presentation. OVA Peptide (257-264) epitope is presented with a differential dependence on the TAP transporter depending on the protein context of the OVA epitope: OVA Peptide (257-264) contained within the MBPCrl-OVA or Crl-OVA bacterial fusion proteins is presented with little dependence on the TAP transporter, while OVA Peptide (257-264) contained within full-length ovalbumin is largely dependent on the TAP transporter, regardless of whether recombinant OVA is expressed in bacteria or the native protein is coupled to polystyrene beads[1]. |
| Cell Assay | TAPl-/- or C57BL/6 macrophages are co-incubated with either bacteria or polystyrene beads containing the 257-264 epitope from ovalbumin [OVA Peptide (257-264)], which binds the mouse class I molecule Kb. The source of the OVA(257-264) epitope is either the Crl-OVA(257-264) (Crl-OVA) fusion protein, the maltose binding protein (MBP)-Crl-OVA fusion protein, native OVA or bacterial recombinant OVA (rOVA); Crl-OVA, MBP-Crl-OVA and rOVA are each expressed in bacteria, and Crl-OVA and MBP-Crl-OVA purified from bacterial lysates and native egg OVA are coated onto polystyrene beads[1]. |
| References |
| Molecular Formula | C47H75F3N10O15 |
|---|---|
| Molecular Weight | 1077.15 |
| InChIKey | BRUCWCULSHVYBQ-VPZPQSBKSA-N |
| SMILES | CCC(C)C(NC(=O)C(N)CO)C(=O)NC(C(=O)NC(CC(N)=O)C(=O)NC(Cc1ccccc1)C(=O)NC(CCC(=O)O)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)O)C(C)CC.O=C(O)C(F)(F)F |