QO 58
Modify Date: 2024-01-02 07:24:21
QO 58 structure
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Common Name | QO 58 | ||
|---|---|---|---|---|
| CAS Number | 1259536-62-3 | Molecular Weight | 443.18 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 568.5±60.0 °C at 760 mmHg | |
| Molecular Formula | C18H8Cl2F4N4O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 297.6±32.9 °C | |
Use of QO 58QO 58 is a potent modulator of K(v)7 channels. QO-58 increases the current amplitudes, shifts the voltage-dependent activation curve in a more negative direction and slows the deactivation of K(v)7.2/K(v)7.3 currents. QO-58 has the potential for the research of diseases associated with neuronal hyperexcitability[1]. |
| Name | QO 58 |
|---|---|
| Synonym | More Synonyms |
| Description | QO 58 is a potent modulator of K(v)7 channels. QO-58 increases the current amplitudes, shifts the voltage-dependent activation curve in a more negative direction and slows the deactivation of K(v)7.2/K(v)7.3 currents. QO-58 has the potential for the research of diseases associated with neuronal hyperexcitability[1]. |
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| Related Catalog | |
| References |
| Density | 1.7±0.1 g/cm3 |
|---|---|
| Boiling Point | 568.5±60.0 °C at 760 mmHg |
| Molecular Formula | C18H8Cl2F4N4O |
| Molecular Weight | 443.18 |
| Flash Point | 297.6±32.9 °C |
| Exact Mass | 442.001129 |
| LogP | 4.92 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.663 |
| 5-(2,6-Dichloro-5-fluoro-3-pyridinyl)-3-phenyl-2-(trifluoromethyl)-pyrazolo[1,5-a]pyrimidin-7(4H)-one |
| Pyrazolo[1,5-a]pyrimidin-7(4H)-one, 5-(2,6-dichloro-5-fluoro-3-pyridinyl)-3-phenyl-2-(trifluoromethyl)- |
| QO-58 |
| 5-(2,6-Dichloro-5-fluoro-3-pyridinyl)-3-phenyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7(4H)-one |