Nusinersen
Modify Date: 2024-01-03 20:22:27
Nusinersen structure
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Common Name | Nusinersen | ||
|---|---|---|---|---|
| CAS Number | 1258984-36-9 | Molecular Weight | 7127.194237 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C234H340N61O128P17S17 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of NusinersenNusinersen is an antisense oligonucleotide drug that modifies pre–messenger RNA splicing of the SMN2 gene and thus promotes increased production of full-length SMN protein[1]. |
| Name | Nusinersen |
|---|---|
| Synonym | More Synonyms |
| Description | Nusinersen is an antisense oligonucleotide drug that modifies pre–messenger RNA splicing of the SMN2 gene and thus promotes increased production of full-length SMN protein[1]. |
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| Related Catalog | |
| In Vitro | Nusinersen is an SMN-ASO that increases SMN levels by blocking an intronic splice silencer in SMN2, thereby facilitating the exon 7 inclusion and generation of FL-SMN2 transcripts[2]. |
| References |
| Molecular Formula | C234H340N61O128P17S17 |
|---|---|
| Molecular Weight | 7127.194237 |
| Storage condition | -20°C |
| Nusinersen |