CHR-3996

Modify Date: 2025-08-23 14:14:21

CHR-3996 Structure
CHR-3996 structure
Common Name CHR-3996
CAS Number 1256448-47-1 Molecular Weight 394.40
Density N/A Boiling Point N/A
Molecular Formula C20H19FN6O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of CHR-3996


Nanatinostat (CHR-3996) is a potent, class I selective and orally active histone deacetylase (HDAC) inhibitor with an IC50 of 8 nM[1].

 Names

Name Nanatinostat

 CHR-3996 Biological Activity

Description Nanatinostat (CHR-3996) is a potent, class I selective and orally active histone deacetylase (HDAC) inhibitor with an IC50 of 8 nM[1].
Related Catalog
Target

IC50:8 nM ( HDAC)[1]

References

[1]. Moffat D, et al. Discovery of 2-(6-{[(6-fluoroquinolin-2-yl)methyl]amino}bicyclo[3.1.0]hex-3-yl)-N-hydroxypyrimidine-5-carboxamide (CHR-3996), a class I selective orally active histone deacetylase inhibitor. J Med Chem. 2010 Dec 23;53(24):8663-78.

 Chemical & Physical Properties

Molecular Formula C20H19FN6O2
Molecular Weight 394.40
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