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57498-96-1

57498-96-1 structure
57498-96-1 structure
  • Name: Carpachromene
  • Chemical Name: 5-Hydroxy-8-(4-hydroxyphenyl)-2,2-dimethyl-2H,6H-pyrano[3,2-g]chr omen-6-one
  • CAS Number: 57498-96-1
  • Molecular Formula: C20H16O5
  • Molecular Weight: 336.34
  • Catalog: Natural product Flavonoids
  • Create Date: 2017-04-29 16:11:44
  • Modify Date: 2025-08-25 17:43:03
  • Carpachromene is a potent α-glucosidase enzyme inhibitor. Carpachromene ameliorates insulin resistance in HepG2 cells via modulating IR/IRS1/PI3k/Akt/GSK3/FoxO1 pathway[1].

Name 5-Hydroxy-8-(4-hydroxyphenyl)-2,2-dimethyl-2H,6H-pyrano[3,2-g]chr omen-6-one
Synonyms Carpachromene
2H,6H-Benzo[1,2-b:5,4-b']dipyran-6-one, 5-hydroxy-8-(4-hydroxyphenyl)-2,2-dimethyl-
Carpachromen
Flemichin B
2S-Lupinifolin
5-Hydroxy-8-(4-hydroxyphenyl)-2,2-dimethyl-2H,6H-pyrano[3,2-g]chromen-6-one
Description Carpachromene is a potent α-glucosidase enzyme inhibitor. Carpachromene ameliorates insulin resistance in HepG2 cells via modulating IR/IRS1/PI3k/Akt/GSK3/FoxO1 pathway[1].
Related Catalog
References

[1]. Alaaeldin R, et al. Carpachromene Ameliorates Insulin Resistance in HepG2 Cells via Modulating IR/IRS1/PI3k/Akt/GSK3/FoxO1 Pathway. Molecules. 2021 Dec 16;26(24):7629.  

Density 1.4±0.1 g/cm3
Boiling Point 562.1±50.0 °C at 760 mmHg
Molecular Formula C20H16O5
Molecular Weight 336.34
Flash Point 205.8±23.6 °C
Exact Mass 336.099762
PSA 79.90000
LogP 4.60
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.660
Storage condition ?20°C
Symbol GHS09
GHS09
Signal Word Warning
Hazard Statements H410
Precautionary Statements P273-P501
Hazard Codes N
Risk Phrases 50
Safety Phrases S61
RIDADR UN 3077 9 / PGIII
Hazard Class 50
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