Alicapistat

Modify Date: 2025-08-26 12:55:04

Alicapistat structure	Common Name	Alicapistat
	CAS Number	1254698-46-8	Molecular Weight	433.50
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₂₇N₃O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Alicapistat

Alicapistat (ABT-957) is an orally active selective inhibitor of human calpains 1 and 2 for the potential use in the treatment of Alzheimer's disease (AD).

Name	Alicapistat

Description	Alicapistat (ABT-957) is an orally active selective inhibitor of human calpains 1 and 2 for the potential use in the treatment of Alzheimer's disease (AD).
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Proteasome Research Areas >> Neurological Disease
Target	Human calpains 1, 2[1].
References	[1]. Lon HK, et al. Pharmacokinetics, Safety, Tolerability, and Pharmacodynamics of Alicapistat, a Selective Inhibitor of Human Calpains 1 and 2 for the Treatment of Alzheimer Disease: An Overview of Phase 1 Studies. Clin Pharmacol Drug Dev. 2018 Jul 27.

Molecular Formula	C₂₅H₂₇N₃O₄
Molecular Weight	433.50
InChIKey	MMLDHJRGTZHNHV-BPGUCPLFSA-N
SMILES	O=C(NC1CC1)C(=O)C(Cc1ccccc1)NC(=O)C1CCC(=O)N1Cc1ccccc1

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Alicapistat
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: Alicapistat (ABT-957)
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

DC Chemicals Limited
China
Product Name: Alicapistat (ABT-957)
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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