Alicapistat

Names

[ Name ]:
Alicapistat

Biological Activity

[Description]:

Alicapistat (ABT-957) is an orally active selective inhibitor of human calpains 1 and 2 for the potential use in the treatment of Alzheimer's disease (AD).

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Proteasome

Research Areas >> Neurological Disease

[Target]

Human calpains 1, 2[1].

[References]

[1]. Lon HK, et al. Pharmacokinetics, Safety, Tolerability, and Pharmacodynamics of Alicapistat, a Selective Inhibitor of Human Calpains 1 and 2 for the Treatment of Alzheimer Disease: An Overview of Phase 1 Studies. Clin Pharmacol Drug Dev. 2018 Jul 27.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₅H₂₇N₃O₄

[ Molecular Weight ]:
433.50

Related Compounds

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