N-Boc-serinol
Modify Date: 2024-01-08 11:37:10
N-Boc-serinol structure
|
Common Name | N-Boc-serinol | ||
|---|---|---|---|---|
| CAS Number | 125414-41-7 | Molecular Weight | 191.225 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 363.0±32.0 °C at 760 mmHg | |
| Molecular Formula | C8H17NO4 | Melting Point | 85-89ºC | |
| MSDS | Chinese USA | Flash Point | 173.4±25.1 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of N-Boc-serinolN-Boc-serinol is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Name | tert-Butyl (1,3-dihydroxypropan-2-yl)carbamate |
|---|---|
| Synonym | More Synonyms |
| Description | N-Boc-serinol is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
Alkyl/ether |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 363.0±32.0 °C at 760 mmHg |
| Melting Point | 85-89ºC |
| Molecular Formula | C8H17NO4 |
| Molecular Weight | 191.225 |
| Flash Point | 173.4±25.1 °C |
| Exact Mass | 191.115753 |
| PSA | 78.79000 |
| LogP | 0.30 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.476 |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H319 |
| Precautionary Statements | P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | R36 |
| Safety Phrases | S26 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2924199090 |
|
~48%
N-Boc-serinol CAS#:125414-41-7 |
| Literature: GE HEALTHCARE AS Patent: WO2009/60021 A1, 2009 ; Location in patent: Page/Page column 21-22 ; |
|
~98%
N-Boc-serinol CAS#:125414-41-7 |
| Literature: Upadhyaya, Dharita J.; Barge, Alessandro; Stefania, Rachele; Cravotto, Giancarlo Tetrahedron Letters, 2007 , vol. 48, # 47 p. 8318 - 8322 |
|
~83%
N-Boc-serinol CAS#:125414-41-7 |
| Literature: Morales-Serna, Jose Antonio; Garcia-Rios, Erendira; Bernal, Jorge; Paleo, Ehecatl; Gavino, Ruben; Cardenas, Jorge Synthesis, 2011 , # 9 art. no. M12811SS, p. 1375 - 1382 |
![[2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-methylsulfonyloxypropyl] methanesulfonate structure](https://www.chemsrc.com/caspic/151/213475-70-8.png)
CAS#:213475-70-8| HS Code | 2924199090 |
|---|---|
| Summary | 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
|
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Macromol. Biosci. 15 , 1206-11, (2015) To find the first restorative treatment for spinal cord injury (SCI), researchers have focused on stem cell therapies. However, one obstacle is the lack of an implantable cell scaffold that can suppor... |
| tert-butyl N-(1,3-dihydroxypropan-2-yl)carbamate |
| 2-Methyl-2-propanyl (1,3-dihydroxy-2-propanyl)carbamate |
| Carbamic acid, N-[2-hydroxy-1-(hydroxymethyl)ethyl]-, 1,1-dimethylethyl ester |
| 1,1-Dimethylethyl [2-hydroxy-1-(hydroxymethyl)ethyl]carbamate |
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: N-Boc-serinol
- Price: ￥116.0/1g ￥456.0/5g ￥756.0/10g ￥46.0/250mg
- Purity: 97.0%
- Stocking Period: 1 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: T-Butyl 1,3-dihydroxypropan-2-ylcarbamate
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: TERT-BUTYL (1,3-DIHYDROXYPROPAN-2-YL)CARBAMATE
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
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