Docetaxal

Modify Date: 2024-01-02 07:33:57

Docetaxal Structure
Docetaxal structure
Common Name Docetaxal
CAS Number 125354-16-7 Molecular Weight 849.916
Density 1.4±0.1 g/cm3 Boiling Point 901.4±65.0 °C at 760 mmHg
Molecular Formula C45H55NO15 Melting Point N/A
MSDS Chinese Flash Point 499.0±34.3 °C

 Use of Docetaxal


Docetaxal (10-Acetyl docetaxel; PNU-101383), an analog of Docetaxel (HY-B0011), is a microtubule disassembly inhibitor, with antimitotic activity. Docetaxal has cytotoxicity for murine leukemic cells[1].

 Names

Name Docetaxel
Synonym More Synonyms

 Docetaxal Biological Activity

Description Docetaxal (10-Acetyl docetaxel; PNU-101383), an analog of Docetaxel (HY-B0011), is a microtubule disassembly inhibitor, with antimitotic activity. Docetaxal has cytotoxicity for murine leukemic cells[1].
Related Catalog
In Vitro Docetaxal has cytotoxicity for murine P388 leukemic cells, with an IC50 of 8.24 μM [1].
References

[1]. Gueritte-Voegelein, et al. Relationships between the structure of taxol analogs and their antimitotic activity. Journal of Medicinal Chemistry, 1991. 34(3), 992–998.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 901.4±65.0 °C at 760 mmHg
Molecular Formula C45H55NO15
Molecular Weight 849.916
Flash Point 499.0±34.3 °C
Exact Mass 849.357178
PSA 230.52000
LogP 7.19
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.606

 Safety Information

HS Code 2932999099

 Synthetic Route

 Customs

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

(2α,5β,7β,10β,13α)-4,10-Diacetoxy-13-({(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl}oxy)-1,7-dihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate
(2α,5β,7β,10β,13α)-4,10-bis(acetyloxy)-13-({(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl}oxy)-1,7-dihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate
N-DEBENZOYL-N-(TERT-BUTOXYCARBONYL)TAXOL
10-Acetyldocetaxel
10-Acetyltaxotere
Docetaxal
Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro -4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-
benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-
DOCETAXOL
(2α,5β,7β,10β,13α)-4,10-Diacetoxy-1,7-dihydroxy-13-{[(2R,3S)-2-hydroxy-3-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-3-phenylpropanoyl]oxy}-9-oxo-5,20-epoxytax-11-en-2-yl benzoate
DOCETAXEL TRIHYDRATE
DOCETAXEL, TRIHYDRATE
DOCETAXEL,TRIHYDRATE
Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: Docetaxal
  • Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao




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