Cholesterol-5α,6α-epoxide
Cholesterol-5α,6α-epoxide structure
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Common Name | Cholesterol-5α,6α-epoxide | ||
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| CAS Number | 1250-95-9 | Molecular Weight | 402.65300 | |
| Density | 1.04g/cm3 | Boiling Point | 497.7ºC at 760mmHg | |
| Molecular Formula | C27H46O2 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 200.9ºC | |
Use of Cholesterol-5α,6α-epoxideCholesterol-5α,6α-epoxide is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
| Name | 5,6α-epoxy-5α-cholestan-3β-ol |
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| Synonym | More Synonyms |
| Description | Cholesterol-5α,6α-epoxide is a biochemical reagent that can be used as a biological material or organic compound for life science related research. |
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| Related Catalog |
| Density | 1.04g/cm3 |
|---|---|
| Boiling Point | 497.7ºC at 760mmHg |
| Molecular Formula | C27H46O2 |
| Molecular Weight | 402.65300 |
| Flash Point | 200.9ºC |
| Exact Mass | 402.35000 |
| PSA | 32.76000 |
| LogP | 6.59990 |
| Vapour Pressure | 5.43E-12mmHg at 25°C |
| Index of Refraction | 1.533 |
| InChIKey | PRYIJAGAEJZDBO-ZEQHCUNVSA-N |
| SMILES | CC(C)CCCC(C)C1CCC2C3CC4OC45CC(O)CCC5(C)C3CCC12C |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
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| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
| RTECS | FZ6360000 |
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Oxysterols: modulators of cholesterol metabolism and other processes.
Physiol. Rev. 80 , 361-554, (2000) Oxygenated derivatives of cholesterol (oxysterols) present a remarkably diverse profile of biological activities, including effects on sphingolipid metabolism, platelet aggregation, apoptosis, and pro... |
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Oxysterols as non-genomic regulators of cholesterol homeostasis.
Trends Endocrinol. Metab. 23 , 99-106, (2012) Tight regulation of cellular and plasma cholesterol is crucial to proper cellular functioning because excess free cholesterol is toxic to cells and is associated with atherosclerosis and heart disease... |
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Surprising unreactivity of cholesterol-5,6-epoxides towards nucleophiles.
J. Lipid Res. 53(4) , 718-25, (2012) We recently established that drugs used for the treatment and the prophylaxis of breast cancers, such as tamoxifen, were potent inhibitors of cholesterol-5,6-epoxide hydrolase (ChEH), which led to the... |
| Cholesterol epoxide |
| 5,6alpha-epoxy-5alpha-cholestan-3beta-ol |
| Cholesterol-5α,6α-epoxide |
| MFCD00046980 |
| Epoxycholesterol |
| cholestanol |
| EINECS 215-007-6 |
| Cholesterol-5alpha,6alpha-epoxide |