syringomycin E
syringomycin E structure
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Common Name | syringomycin E | ||
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| CAS Number | 124888-22-8 | Molecular Weight | 1225.78000 | |
| Density | 1.47g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C53H85ClN14O17 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of syringomycin ESyringomycin E is an antifungal cyclic lipodepsinonapeptide. Syringomycin E exhibits growth inhibition of Saccharomyces cerevisiae through interaction with the plasma membrane. Syringomycin E causes K+ efflux, Ca2+ influx, and changes in membrane potential, and is related to channel formation[1][2]. |
| Name | syringomycin E |
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| Synonym | More Synonyms |
| Description | Syringomycin E is an antifungal cyclic lipodepsinonapeptide. Syringomycin E exhibits growth inhibition of Saccharomyces cerevisiae through interaction with the plasma membrane. Syringomycin E causes K+ efflux, Ca2+ influx, and changes in membrane potential, and is related to channel formation[1][2]. |
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| Related Catalog | |
| In Vitro | Syringomycin E (0.5 μg/mL, 1 μg/mL; 48 h) 对酿酒酵母菌株 SS33 和 SS56 有抑制作用[1]。 Syringomycin E 是一种离子通道型，对电势跨膜分布的变化敏感[2]。 |
| References |
| Density | 1.47g/cm3 |
|---|---|
| Molecular Formula | C53H85ClN14O17 |
| Molecular Weight | 1225.78000 |
| Exact Mass | 1224.59000 |
| PSA | 522.86000 |
| LogP | 0.18720 |
| Index of Refraction | 1.641 |
| InChIKey | YMFYPHGOLKNWQN-AQLQTECXSA-N |
| SMILES | CCC=C1NC(=O)C(Cc2ccccc2)NC(=O)C(CCCN=C(N)N)NC(=O)C(CCN)NC(=O)C(CCN)NC(=O)C(CO)NC(=O)C(NC(=O)CC(O)CCCCCCCC)COC(=O)C(C(O)CCl)NC(=O)C(C(O)C(=O)O)NC1=O |
| Personal Protective Equipment | Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US) |
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| RIDADR | NONH for all modes of transport |
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Change in activity of serine palmitoyltransferase affects sensitivity to syringomycin E in yeast Saccharomyces cerevisiae.
FEMS Microbiol. Lett. 358(1) , 64-71, (2014) Syringomycin E is a cyclic lipodepsipeptide produced by strains of the plant bacterium Pseudomonas syringae pv. syringae. Genetic studies involving the yeast Saccharomyces cerevisiae have revealed tha... |
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Effect of agents modifying the membrane dipole potential on properties of syringomycin E channels.
Langmuir 23(13) , 6889-92, (2007) We evaluated the effect of agents modifying the membrane dipole potential: phloretin, 6-ketocholestanol and RH 421 on the properties of single channels formed by lipodepsipeptide syringomycin E (SRE) ... |
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[Transport of large organic ions through syringomycin channels in the membranes containing dipole modifiers].
Tsitologiia 53(5) , 450-6, (2011) The effect of the membrane dipole potential (Phid) on a conductance and a steady-state number of functioning channels formed by cyclic lipodepsipeptide syringomycin E (SRE) in bilayer lipid membranes ... |
| SYRINGOMYCIN E FROM PSEUDOMONAS SYRINGAE B-301D |
| syringomycin-E |