Folate-PEG3-alkyne

Modify Date: 2024-01-10 09:12:38

Folate-PEG3-alkyne Structure
Folate-PEG3-alkyne structure
Common Name Folate-PEG3-alkyne
CAS Number 1245285-73-7 Molecular Weight 610.62
Density N/A Boiling Point N/A
Molecular Formula C28H34N8O8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Folate-PEG3-alkyne


Folate-PEG3-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Folate-PEG3-alkyne

 Folate-PEG3-alkyne Biological Activity

Description Folate-PEG3-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C28H34N8O8
Molecular Weight 610.62