Diazo Biotin-PEG3-alkyne

Modify Date: 2025-09-13 00:50:49

Diazo Biotin-PEG3-alkyne Structure
Diazo Biotin-PEG3-alkyne structure
Common Name Diazo Biotin-PEG3-alkyne
CAS Number 1884349-58-9 Molecular Weight 795.94
Density N/A Boiling Point N/A
Molecular Formula C39H53N7O9S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Diazo Biotin-PEG3-alkyne


Diazo Biotin-PEG3-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Diazo Biotin-PEG3-alkyne
Synonym More Synonyms

 Diazo Biotin-PEG3-alkyne Biological Activity

Description Diazo Biotin-PEG3-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C39H53N7O9S
Molecular Weight 795.94
InChIKey AIUZFZDETVBCLH-OHTDSXDOSA-N
SMILES C#CCOCCC(=O)NCCc1ccc(O)c(N=Nc2ccc(C(=O)NCCOCCOCCOCCNC(=O)CCCCC3SCC4NC(=O)NC43)cc2)c1

 Synonyms

MFCD28505544
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