Biotin-PEG3-SH

Modify Date: 2024-01-14 16:08:15

Biotin-PEG3-SH Structure
Biotin-PEG3-SH structure
Common Name Biotin-PEG3-SH
CAS Number 1244028-52-1 Molecular Weight 435.60
Density N/A Boiling Point N/A
Molecular Formula C18H33N3O5S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Biotin-PEG3-SH


Biotin-PEG3-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Biotin-PEG3-SH

 Biotin-PEG3-SH Biological Activity

Description Biotin-PEG3-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C18H33N3O5S2
Molecular Weight 435.60