2-Amino-2-methyl-1-propanol

Modify Date: 2025-08-21 20:53:30

2-Amino-2-methyl-1-propanol structure	Common Name	2-Amino-2-methyl-1-propanol
	CAS Number	124-68-5	Molecular Weight	89.14
	Density	0.9±0.1 g/cm3	Boiling Point	167.2±13.0 °C at 760 mmHg
	Molecular Formula	C₄H₁₁NO	Melting Point	24-28 °C(lit.)
	MSDS	Chinese USA	Flash Point	67.2±0.0 °C
	Symbol	GHS05	Signal Word	Danger

Use of 2-Amino-2-methyl-1-propanol

2-Amino-2-methyl-1-propanol (AMP) is a neutralizer, buffer and surfactant[1].

Name	2-Amino-2-methyl-1-propanol
Synonym	More Synonyms

Description	2-Amino-2-methyl-1-propanol (AMP) is a neutralizer, buffer and surfactant[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
References	[1]. Hong NS, et al. Rapid and accurate determination of deoxyribonucleoside monophosphates from DNA using micellar electrokinetic chromatography with a cationic surfactant additive. Anal Bioanal Chem. 2011 Jun;400(7):2131-40.

Density	0.9±0.1 g/cm3
Boiling Point	167.2±13.0 °C at 760 mmHg
Melting Point	24-28 °C(lit.)
Molecular Formula	C₄H₁₁NO
Molecular Weight	89.14
Flash Point	67.2±0.0 °C
Exact Mass	89.084061
PSA	46.25000
LogP	-0.61
Vapour density	3 (vs air)
Vapour Pressure	0.6±0.7 mmHg at 25°C
Index of Refraction	1.447
Storage condition	Store at RT.
Stability	Stable. Combustible. Incompatible with strong oxidizing agents. May present an explosion hazard if heated.
Water Solubility	miscible

2-Amino-2-methyl-1-propanol MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UA5950000

CHEMICAL NAME :: 1-Propanol, 2-amino-2-methyl-

CAS REGISTRY NUMBER :: 124-68-5

BEILSTEIN REFERENCE NO. :: 0505979

LAST UPDATED :: 199701

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C4-H11-N-O

MOLECULAR WEIGHT :: 89.16

WISWESSER LINE NOTATION :: ZX1&1&1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2900 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 9(2),203,1990

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 9(2),203,1990

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - coma Lungs, Thorax, or Respiration - respiratory stimulation

REFERENCE :: JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 22,315,1940 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 44800 mg/kg/8W-C

TOXIC EFFECTS :: Liver - other changes Skin and Appendages - hair Related to Chronic Data - death

REFERENCE :: JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 9(2),203,1990

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 230 ug/m3/4H/13W-I

TOXIC EFFECTS :: Cardiac - changes in heart weight Lungs, Thorax, or Respiration - changes in lung weight Related to Chronic Data - changes in uterine weight

REFERENCE :: JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 9(2),203,1990

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 11340 mg/kg/28D-C

TOXIC EFFECTS :: Behavioral - food intake (animal) Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases

REFERENCE :: JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 9(2),203,1990

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Primate - monkey

DOSE/DURATION :: 6 mg/m3/89D-I

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - respiratory depression Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 9(2),203,1990

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - hamster

DOSE/DURATION :: 100 mg/m3/4H/13W-I

TOXIC EFFECTS :: Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 9(2),203,1990 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M5222 No. of Facilities: 2958 (estimated) No. of Industries: 28 No. of Occupations: 44 No. of Employees: 24640 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M5222 No. of Facilities: 16965 (estimated) No. of Industries: 136 No. of Occupations: 94 No. of Employees: 219300 (estimated) No. of Female Employees: 54846 (estimated)

Symbol	GHS05
Signal Word	Danger
Hazard Statements	H315-H318-H412
Precautionary Statements	P273-P280-P305 + P351 + P338 + P310
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xi:Irritant
Risk Phrases	R36/38;R52/53
Safety Phrases	S61
RIDADR	2735
WGK Germany	1
RTECS	UA5950000
Packaging Group	III
HS Code	2922199090

Precursor 9
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DownStream 10
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HS Code	2922199090
Summary	2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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2-Amino-2-methyl-1-propanol

2,2-Dimethyl-ethanolamine

EINECS 204-709-8

2-Amino-2-methyl-propan-1-ol

2-Amino-2-Methylpropan-1-Ol

MFCD00008051

Aminomethyl propanol

1,1-Dimethyl-2-hydroxyethylamine

1-Propanol, 2-amino-2-methyl-

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