ADR 851

Modify Date: 2025-09-18 16:16:16

Use of ADR 851

ADR 851 is a dopamine D2 receptor antagonist,and can be used in research on antiemetics[1].

Name	4-amino-5-chloro-N-[[(2S)-pyrrolidin-2-yl]methyl]-2,3-dihydro-1-benzofuran-7-carboxamide,hydrochloride
Synonym	More Synonyms

Description	ADR 851 is a dopamine D2 receptor antagonist,and can be used in research on antiemetics[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Research Areas >> Neurological Disease
References	[1]. Monković I, et al. 7 Developments in the Antiemetic Area: Chemistry, Pharmacology and Therapy[J]. Progress in medicinal chemistry, 1990, 27: 297-323.

Boiling Point	423.2ºC at 760mmHg
Molecular Formula	C₁₄H₁₉Cl₂N₃O₂
Molecular Weight	332.22600
Flash Point	209.7ºC
Exact Mass	331.08500
PSA	79.87000
LogP	3.62570
Vapour Pressure	2.28E-07mmHg at 25°C
InChIKey	PCBGZTCWZUGEJX-QRPNPIFTSA-N
SMILES	Cl.Nc1c(Cl)cc(C(=O)NCC2CCCN2)c2c1CCO2

7-Benzofurancarboxamide,4-amino-5-chloro-2,3-dihydro-N-(2-pyrrolidinylmethyl)-,monohydrochloride,(S)

Adr 851

4-amino-5-chloro-N-[[(2S)-pyrrolidin-2-yl]methyl]-2,3-dihydro-1-benzofuran-7-carboxamide hydrochloride

4-Amino-5-chloro-N-(2-pyrrolidinylmethyl)-2,3-dihydrobenzofuran-7-carboxamide hcl