Boc-Aminooxy-PEG3-azide

Modify Date: 2024-01-28 08:32:57

Boc-Aminooxy-PEG3-azide Structure
Boc-Aminooxy-PEG3-azide structure
Common Name Boc-Aminooxy-PEG3-azide
CAS Number 1235514-15-4 Molecular Weight 334.369
Density N/A Boiling Point N/A
Molecular Formula C13H26N4O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Boc-Aminooxy-PEG3-azide


Boc-Aminooxy-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name t-Boc-Aminoxy-PEG3-Azide
Synonym More Synonyms

 Boc-Aminooxy-PEG3-azide Biological Activity

Description Boc-Aminooxy-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Zhao B, et al. Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond. Pharmacol Rev. 2020 Apr;72(2):380-413.

 Chemical & Physical Properties

Molecular Formula C13H26N4O6
Molecular Weight 334.369
Exact Mass 334.185242
LogP 0.98

 Synonyms

Carbamic acid, N-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]-, 1,1-dimethylethyl ester
MFCD28950781
2-Methyl-2-propanyl (2-{2-[2-(2-azidoethoxy)ethoxy]ethoxy}ethoxy)carbamate
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