Paederosidic acid methyl ester

Modify Date: 2025-08-29 10:21:03

Paederosidic acid methyl ester Structure
Paederosidic acid methyl ester structure
Common Name Paederosidic acid methyl ester
CAS Number 122413-01-8 Molecular Weight 478.467
Density 1.6±0.1 g/cm3 Boiling Point 711.2±70.0 °C at 760 mmHg
Molecular Formula C19H26O12S Melting Point N/A
MSDS N/A Flash Point 383.9±35.7 °C

 Use of Paederosidic acid methyl ester


Paederosidic acid methyl ester is a ATP‐sensitive K+ channel activator, isolated from P. scandens. Paederosidic acid methyl ester exhibits significant central analgesic activity, and enhances the threshold of pain by activating ATP‐sensitive K+ channel in the brain and spinal cord level[1].

 Names

Name Methyl (1S,4aS,5S,7aS)-1-(β-D-glucopyranosyloxy)-5-hydroxy-7-({[( methylsulfanyl)carbonyl]oxy}methyl)-1,4a,5,7a-tetrahydrocyclopent a[c]pyran-4-carboxylate
Synonym More Synonyms

 Paederosidic acid methyl ester Biological Activity

Description Paederosidic acid methyl ester is a ATP‐sensitive K+ channel activator, isolated from P. scandens. Paederosidic acid methyl ester exhibits significant central analgesic activity, and enhances the threshold of pain by activating ATP‐sensitive K+ channel in the brain and spinal cord level[1].
Related Catalog
Target

IC50: K+ channel[1]

References

[1]. Chen YF,et al.Possible mechanism involved in the antinociceptive activity of dimer of paederosidic acid and paederosidic acid methyl ester in mice.CNS Neurosci Ther. 2014 Feb;20(2):188-90.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 711.2±70.0 °C at 760 mmHg
Molecular Formula C19H26O12S
Molecular Weight 478.467
Flash Point 383.9±35.7 °C
Exact Mass 478.114502
PSA 206.74000
LogP -1.72
Vapour Pressure 0.0±5.2 mmHg at 25°C
Index of Refraction 1.634

 Safety Information

Hazard Codes Xi

 Synonyms

Cyclopenta[c]pyran-4-carboxylic acid, 1-(β-D-glucopyranosyloxy)-1,4a,5,7a-tetrahydro-5-hydroxy-7-[[[(methylthio)carbonyl]oxy]methyl]-, methyl ester, (1S,4aS,5R,7aS)-
Methyl (1S,4aS,5S,7aS)-1-(β-D-glucopyranosyloxy)-5-hydroxy-7-({[(methylsulfanyl)carbonyl]oxy}methyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate
paederosidic acid methyl ester
Cyclopenta[c]pyran-4-carboxylic acid, 1-(β-D-glucopyranosyloxy)-1,4a,5,7a-tetrahydro-5-hydroxy-7-[[[(methylthio)carbonyl]oxy]methyl]-, methyl ester, (1S,4aS,5S,7aS)-
Methyl (1S,4aS,5R,7aS)-1-(β-D-glucopyranosyloxy)-5-hydroxy-7-({[(methylsulfanyl)carbonyl]oxy}methyl)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-4-carboxylate
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