Phenoxyethanol-d4

Modify Date: 2024-02-24 09:34:42

Phenoxyethanol-d4 Structure
Phenoxyethanol-d4 structure
Common Name Phenoxyethanol-d4
CAS Number 1219804-65-5 Molecular Weight 142.188447112
Density N/A Boiling Point N/A
Molecular Formula C8H6D4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Phenoxyethanol-d4


Phenoxyethanol-d4 is the deuterium labeled Phenoxyethanol[1]. Phenoxyethanol has a broad spectrum of antimicrobial activity against various gram-negative and gram-positive bacteria. Phenoxyethanol is an uncouple agent in oxidative phosphorylation from respiration and competitively inhibits malate dehydrogenase. Phenoxyethanol is used as a preservative in cosmetic, vaccine, and textile, et al[2].

 Names

Name 2-Phenoxyethyl--d4 Alcohol

 Phenoxyethanol-d4 Biological Activity

Description Phenoxyethanol-d4 is the deuterium labeled Phenoxyethanol[1]. Phenoxyethanol has a broad spectrum of antimicrobial activity against various gram-negative and gram-positive bacteria. Phenoxyethanol is an uncouple agent in oxidative phosphorylation from respiration and competitively inhibits malate dehydrogenase. Phenoxyethanol is used as a preservative in cosmetic, vaccine, and textile, et al[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. B Dréno, et al. Safety Review of Phenoxyethanol When Used as a Preservative in Cosmetics. J Eur Acad Dermatol Venereol. 2019 Nov;33 Suppl 7:15-24.  

 Chemical & Physical Properties

Molecular Formula C8H6D4O2
Molecular Weight 142.188447112