Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Phenoxyethanol
Price: ￥88.0/500g
Purity: 98.0%
Stocking Period: Inquiry
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Phenoxyethanol
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 2-Phenoxyethanol
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Zhejiang Hangyu API Co., Ltd
China
Product Name: Ethylene Glycol Monophenyl Ether
Price: ￥Inquiry/1kg
Purity: 99.5%
Stocking Period: Inquiry
Contact: Vinnie

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Phenoxyethanol
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Stocking Period: Inquiry
Contact: Anson

122-99-6

122-99-6 structure

Name: Phenoxyethanol
Chemical Name: 2-phenoxyethanol
CAS Number: 122-99-6
Molecular Formula: C₈H₁₀O₂
Molecular Weight: 138.164
Catalog: API Synthetic anti-infective drugs Disinfectant antiseptic
Create Date: 2018-02-05 08:00:00
Modify Date: 2024-01-01 19:38:02
Phenoxyethanol has a broad spectrum of antimicrobial activity against various gram-negative and gram-positive bacteria. Phenoxyethanol is an uncouple agent in oxidative phosphorylation from respiration and competitively inhibits malate dehydrogenase. Phenoxyethanol is used as a preservative in cosmetic, vaccine, and textile, et al[1].

Name	2-phenoxyethanol
Synonyms	Phenoxytol MFCD00046644 Ethylene glycol monophenyl ether PHENOXETOL PHENOXYETHYL ALCOHOL Phenylglycol emery6705 Dowanol EP 2-hydroxyethyl phenyl ether dowanoleph phenoxy ethanol 2-Phenoxyethanol 2-phenyloxyethanol EINECS 204-589-7 2-phenoxyethan-1-ol Arosol Phenyl cellosolve Rose ether Ethylene glycol monophenyl ether,PHE-G,PHE-S Ethanol, 2-phenoxy- 1-Hydroxy-2-phenoxyethane 2-Phenoxy-ethanol

Description	Phenoxyethanol has a broad spectrum of antimicrobial activity against various gram-negative and gram-positive bacteria. Phenoxyethanol is an uncouple agent in oxidative phosphorylation from respiration and competitively inhibits malate dehydrogenase. Phenoxyethanol is used as a preservative in cosmetic, vaccine, and textile, et al[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. B Dréno, et al. Safety Review of Phenoxyethanol When Used as a Preservative in Cosmetics. J Eur Acad Dermatol Venereol. 2019 Nov;33 Suppl 7:15-24.

Density	1.1±0.1 g/cm3
Boiling Point	245.2±0.0 °C at 760 mmHg
Melting Point	11-13 °C
Molecular Formula	C₈H₁₀O₂
Molecular Weight	138.164
Flash Point	105.3±14.1 °C
Exact Mass	138.068085
PSA	29.46000
LogP	1.16
Vapour density	4.8 (vs air)
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.526
Storage condition	room temp
Water Solubility	30 g/L (20 ºC)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KM0350000

CHEMICAL NAME :: Ethanol, 2-phenoxy-

CAS REGISTRY NUMBER :: 122-99-6

BEILSTEIN REFERENCE NO. :: 1364011

LAST UPDATED :: 199710

DATA ITEMS CITED :: 22

MOLECULAR FORMULA :: C8-H10-O2

MOLECULAR WEIGHT :: 138.18

WISWESSER LINE NOTATION :: Q2OR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1260 mg/kg

TOXIC EFFECTS :: Behavioral - general anesthetic Gastrointestinal - other changes Kidney, Ureter, Bladder - other changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 14422 mg/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - acute pulmonary edema

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 554 mg/kg

TOXIC EFFECTS :: Brain and Coverings - other degenerative changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 933 mg/kg

TOXIC EFFECTS :: Brain and Coverings - other degenerative changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 490 mg/kg

TOXIC EFFECTS :: Brain and Coverings - other degenerative changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 5 mL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 182 gm/kg/13W-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - changes in bladder weight Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 17500 mg/kg/14D-I

TOXIC EFFECTS :: Gastrointestinal - alteration in gastric secretion Blood - other changes Related to Chronic Data - death

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 15 mg/m3/9W-I

TOXIC EFFECTS :: Brain and Coverings - recordings from specific areas of CNS Behavioral - somnolence (general depressed activity) Liver - liver function tests impaired

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 3 gm/kg/10D-I

TOXIC EFFECTS :: Behavioral - general anesthetic Kidney, Ureter, Bladder - other changes in urine composition Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 14 gm/kg/14D-I

TOXIC EFFECTS :: Blood - other changes Related to Chronic Data - death

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Bacteria - Escherichia coli

DOSE/DURATION :: 2000 ppm

REFERENCE :: MCBIA7 Microbios. (Faculty Press, 88 Regent St., Cambridge, UK) V.1- 1969- Volume(issue)/page/year: 28,7,1980 *** REVIEWS *** TOXICOLOGY REVIEW FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 13,747,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83449 No. of Facilities: 711 (estimated) No. of Industries: 18 No. of Occupations: 19 No. of Employees: 9560 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83449 No. of Facilities: 5523 (estimated) No. of Industries: 63 No. of Occupations: 77 No. of Employees: 111040 (estimated) No. of Female Employees: 46637 (estimated)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H319
Precautionary Statements	P301 + P312 + P330-P305 + P351 + P338
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xn:Harmful
Risk Phrases	R22;R36
Safety Phrases	S26
RIDADR	NONH for all modes of transport
WGK Germany	1
RTECS	KM0350000
HS Code	29094990

Precursor 9
122-59-8 2555-49-9 107-07-3 108-95-2
96-49-1 540-51-2 41532-81-4 2065-23-8
29279-13-8
DownStream 10
3598-16-1 139-02-6 34743-88-9 34743-89-0
493-09-4 57744-67-9 29639-77-8 34743-87-8
22855-36-3 37421-04-8

HS Code	2909499000
Summary	2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

122-99-6	13138-67-5
56101-99-6	56257-90-0
21273-38-1	1219804-65-5
6161-86-0	185527-77-9
909731-21-1	18168-30-4