4-Hydroxypropranolol D7 hydrochloride

Modify Date: 2025-08-26 13:20:43

4-Hydroxypropranolol D7 hydrochloride structure	Common Name	4-Hydroxypropranolol D7 hydrochloride
	CAS Number	1219804-03-1	Molecular Weight	282.386
	Density	1.2±0.1 g/cm3	Boiling Point	487.5±35.0 °C at 760 mmHg
	Molecular Formula	C₁₆H₁₅D₇ClNO₃	Melting Point	N/A
	MSDS	N/A	Flash Point	248.6±25.9 °C

Use of 4-Hydroxypropranolol D7 hydrochloride

4-Hydroxypropranolol D7 hydrochloride ((±)-4-hydroxy Propranolol D7 hydrochloride) is a deuterium labeled 4-Hydroxypropranolol hydrochloride. 4-Hydroxypropranolol hydrochlorid is an active metabolite of Propranolol, with potency comparable to Propranolol. 4-Hydroxypropranolol hydrochlorid inhibits β1- and β2-adrenergic receptors with pA2 values of 8.24 and 8.26, respectively. 4-Hydroxypropranolol hydrochlorid has intrinsic sympathomimetic activity, membrane stabilizing activity and potent antioxidant properties[1][2][3].

Name	4-[3-(1,1,1,2,3,3,3-heptadeuteriopropan-2-ylamino)-2-hydroxypropoxy]naphthalen-1-ol,hydrochloride
Synonym	More Synonyms

Description	4-Hydroxypropranolol D7 hydrochloride ((±)-4-hydroxy Propranolol D7 hydrochloride) is a deuterium labeled 4-Hydroxypropranolol hydrochloride. 4-Hydroxypropranolol hydrochlorid is an active metabolite of Propranolol, with potency comparable to Propranolol. 4-Hydroxypropranolol hydrochlorid inhibits β1- and β2-adrenergic receptors with pA2 values of 8.24 and 8.26, respectively. 4-Hydroxypropranolol hydrochlorid has intrinsic sympathomimetic activity, membrane stabilizing activity and potent antioxidant properties[1][2][3].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor Research Areas >> Neurological Disease
Target	pA2: 8.24 (β1-adrenergic receptor) and 8.26 (β2-adrenergic receptor)[2]
References	[1]. Fitzgerald JD, et al. Pharmacology of 4-hydroxypropranolol, a metabolite of propranolol. Br J Pharmacol. 1971 Sep;43(1):222-35. [2]. Nelson WL, et al. The 3,4-catechol derivative of propranolol, a minor dihydroxylated metabolite. J Med Chem. 1984 Jul;27(7):857-61. [3]. Ivan Tong Mak, et al. Potent Antioxidant Properties of 4-Hydroxyl-propranolol. Journal of Pharmacology and Experimental Therapeutics. 2004, 308(1):85-90.

Density	1.2±0.1 g/cm3
Boiling Point	487.5±35.0 °C at 760 mmHg
Molecular Formula	C₁₆H₁₅D₇ClNO₃
Molecular Weight	282.386
Flash Point	248.6±25.9 °C
Exact Mass	282.196075
PSA	61.72000
LogP	2.27
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.602

1-Naphthalenol, 4-[2-hydroxy-3-[[1-(methyl-d)ethyl-1,2,2,2-d]amino]propoxy]-

4-{2-Hydroxy-3-[(H)-2-propanylamino]propoxy}-1-naphthol

[2H7]-4-Hydroxypropranolol hydrochloride

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4-Hydroxypropranolol D7 hydrochloride

Use of 4-Hydroxypropranolol D7 hydrochloride

Names

4-Hydroxypropranolol D7 hydrochloride Biological Activity

Chemical & Physical Properties

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.