L-Epinephrine-d3

Modify Date: 2024-01-08 17:54:11

L-Epinephrine-d3 Structure
L-Epinephrine-d3 structure
Common Name L-Epinephrine-d3
CAS Number 1217733-17-9 Molecular Weight 186.22
Density N/A Boiling Point N/A
Molecular Formula C9H10D3NO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of L-Epinephrine-d3


L-Epinephrine-d3 is deuterium labeled L-Epinephrine. L-Epinephrine is a hormone secreted by the medulla of the adrenal glands. L-Epinephrine is an α-adrenergic and β-adrenergic receptor agonist.

 Names

Name 4-[(1R)-1-hydroxy-2-(trideuteriomethylamino)ethyl]benzene-1,2-diol
Synonym More Synonyms

 L-Epinephrine-d3 Biological Activity

Description L-Epinephrine-d3 is deuterium labeled L-Epinephrine. L-Epinephrine is a hormone secreted by the medulla of the adrenal glands. L-Epinephrine is an α-adrenergic and β-adrenergic receptor agonist.
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Alm A, et al. The effect of topical l-epinephrine on regional ocular blood flow in monkeys. Invest Ophthalmol Vis Sci. 1980 May;19(5):487-91.

[3]. Simons FE, et al. First-aid treatment of anaphylaxis to food: focus on epinephrine. J Allergy Clin Immunol. 2004 May;113(5):837-44.

[4]. Morris KA, et al. Epinephrine and glucose modulate training-related CREB phosphorylation in old rats: relationships to age-related memory impairments. Exp Gerontol. 2013 Feb;48(2):115-27.

[5]. Callaway CW, et al. Epinephrine for cardiac arrest. Curr Opin Cardiol. 2013 Jan;28(1):36-42.

 Chemical & Physical Properties

Molecular Formula C9H10D3NO3
Molecular Weight 186.22
Exact Mass 186.10800
PSA 72.72000
LogP 0.74150
Storage condition -20°C

 Synonyms

Adrenaline-d3
Renoform-d3
Adrenalin-d3
[2H3]-Adrenaline
Levoepinephrine-d3
Renostypticin-d3
L-(-)-Epinephrine-d3
Adnephrine-d3
Adrenal-d3