FTI 276 TFA

Modify Date: 2025-08-27 09:19:02

FTI 276 TFA Structure
FTI 276 TFA structure
Common Name FTI 276 TFA
CAS Number 1217471-51-6 Molecular Weight 547.61
Density N/A Boiling Point N/A
Molecular Formula C23H28F3N3O5S2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of FTI 276 TFA


FTI-276 is a protein farnesyl transferase (PFT) inhibitor with IC50s of 0.9 nM and 0.5 nM for Plasmodium falciparum and human, respectively[1].

 Names

Name FTI 276 TFA

 FTI 276 TFA Biological Activity

Description FTI-276 is a protein farnesyl transferase (PFT) inhibitor with IC50s of 0.9 nM and 0.5 nM for Plasmodium falciparum and human, respectively[1].
Related Catalog
Target

IC50: 0.9 nM (PFT, Plasmodium falciparum), 0.5 nM (PFT, human)[1].

References

[1]. Chakrabarti D, et al. Protein farnesyltransferase and protein prenylation in Plasmodium falciparum.J Biol Chem. 2002 Nov 1; 277(44):42066-73. Epub 2002 Aug 22.

 Chemical & Physical Properties

Molecular Formula C23H28F3N3O5S2
Molecular Weight 547.61
InChIKey IAVHISGQCODLHL-WSCVZUBPSA-N
SMILES CSCCC(NC(=O)c1ccc(NCC(N)CS)cc1-c1ccccc1)C(=O)O.O=C(O)C(F)(F)F
Storage condition 2-8℃
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