3,3'-Diiodo-L-thyronine-13C6

Modify Date: 2024-01-01 23:59:37

3,3'-Diiodo-L-thyronine-13C6 structure	Common Name	3,3'-Diiodo-L-thyronine-13C6
	CAS Number	1217459-13-6	Molecular Weight	531.03300
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₅H₁₃I₂NO₄	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	N/A
	Symbol	GHS07	Signal Word	Warning

Use of 3,3'-Diiodo-L-thyronine-13C6

3,3'-Diiodo-L-thyronine-13C6 is the 13C labeled 3,3'-Diiodo-L-thyronine[1]. 3,3'-Diiodo-L-thyronine (3,3'-T2) is an endogenous metabolite of thyroid hormone. 3,3'-Diiodo-L-thyronine significantly enhances COX activity[2][3].

Name	(2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3-iodophenyl]propanoic acid
Synonym	More Synonyms

Description	3,3'-Diiodo-L-thyronine-13C6 is the 13C labeled 3,3'-Diiodo-L-thyronine[1]. 3,3'-Diiodo-L-thyronine (3,3'-T2) is an endogenous metabolite of thyroid hormone. 3,3'-Diiodo-L-thyronine significantly enhances COX activity[2][3].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> COX Research Areas >> Metabolic Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Lorenzini L, et al. Assay of Endogenous 3,5-diiodo-L-thyronine (3,5-T2) and 3,3'-diiodo-L-thyronine (3,3'-T2) in Human Serum: A Feasibility Study. Front Endocrinol (Lausanne). 2019 Feb 19;10:88. [3]. Lanni A, et al. Rapid stimulation in vitro of rat liver cytochrome oxidase activity by 3,5-diiodo-L-thyronine and by 3,3'-diiodo-L-thyronine. Mol Cell Endocrinol. 1994 Feb99(1):89-94. [4]. Chen X, et al. Simultaneous quantification of T4, T3, rT3, 3,5-T2 and 3,3'-T2 in larval zebrafish (Danio rerio) as a model to study exposure to polychlorinated biphenyls. Biomed Chromatogr. 2018 Jun32(6):e4185.

Molecular Formula	C₁₅H₁₃I₂NO₄
Molecular Weight	531.03300
Exact Mass	530.91400
PSA	92.78000
LogP	4.04840

3,3'-Diiodo-L-thyronine-13C6 MSDS(Chinese)

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302
RIDADR	NONH for all modes of transport

3,3 inverted exclamation marka-Diiodo-L-thyronine-(phenoxy-13C6) (T2)

T2-13C6

3,3'-Diiodo-L-thyronine-13C6

Use of 3,3'-Diiodo-L-thyronine-13C6

Names

3,3'-Diiodo-L-thyronine-13C6 Biological Activity

Chemical & Physical Properties

MSDS

Safety Information

Synonyms