Big Endothelin-1 (1-39), porcine
Modify Date: 2024-01-02 09:30:58
Big Endothelin-1 (1-39), porcine structure
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Common Name | Big Endothelin-1 (1-39), porcine | ||
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| CAS Number | 120796-99-8 | Molecular Weight | N/A | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C193H289N49O58S5 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of Big Endothelin-1 (1-39), porcineBig Endothelin-1 (1-39), porcine is the precursor of endothelin-1. Endothelin-1 (ET-1) is a potent vasopressor peptide. Big Endothelin-1 (1-39), porcine has similar pressor effects in vivo[1]. |
| Name | H-CYS-SER-CYS-SER-SER-LEU-MET-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-VAL-ASN-THR-PRO-GLU-HIS-ILE-VAL-PRO-TYR-GLY-LEU-GLY-SER-PRO-SER-ARG-SER-OH |
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| Synonym | More Synonyms |
| Description | Big Endothelin-1 (1-39), porcine is the precursor of endothelin-1. Endothelin-1 (ET-1) is a potent vasopressor peptide. Big Endothelin-1 (1-39), porcine has similar pressor effects in vivo[1]. |
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| Related Catalog | |
| In Vitro | Endothelin-1 (ET-1) is a potent, endothelial cell-derived, 21-amino acid peptide that has potent vasoconstricting properties and may participate in the regulation of blood pressure and regional blood flow[1]. |
| In Vivo | Big Endothelin-1 (1-39), porcine, the cDNA deduced putative precursor of ET-1, has been reported to have similar pressor effects in vivo[1]. |
| References |
| Molecular Formula | C193H289N49O58S5 |
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| Storage condition | −20°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
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A novel potent vasoconstrictor peptide produced by vascular endothelial cells.
Nature 332 , 411, (1988) An endothelium-derived 21-residue vasoconstrictor peptide, endothelin, has been isolated, and shown to be one of the most potent vasoconstrictors known. Cloning and sequencing of preproendothelin comp... |
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Cloning and sequence analysis of cDNA encoding the precursor of a human endothelium-derived vasoconstrictor peptide, endothelin: identity of human and porcine endothelin.
FEBS Lett. 231 , 440, (1988) A cDNA encoding a human endothelium-derived vasoconstrictor peptide, endothelin, was isolated from a human placenta cDNA library. The nucleotide sequence of this cDNA clone showed that the primary str... |
| CYS-SER-CYS-SER-SER-LEU-MET-ASP-LYS-GLU-CYS-VAL-TYR-PHE-CYS-HIS-LEU-ASP-ILE-ILE-TRP-VAL-ASN-THR-PRO-GLU-HIS-ILE-VAL-PRO-TYR-GLY-LEU-GLY-SER-PRO-SER-ARG-SER |