broflanilide
Modify Date: 2024-01-02 11:26:13
broflanilide structure
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Common Name | broflanilide | ||
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| CAS Number | 1207727-04-5 | Molecular Weight | 663.277 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 467.9±45.0 °C at 760 mmHg | |
| Molecular Formula | C25H14BrF11N2O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 236.8±28.7 °C | |
Use of broflanilideBroflanilide is a potential insecticide and metabolized to desmethyl-broflanilide, which is a potent antagonist at the insect resistant-to-dieldrin (RDL) GABA receptor, and inhibits S. litura RDL GABAR, with an IC50 value of 1.3 nM. |
| Name | broflanilide |
|---|---|
| Synonym | More Synonyms |
| Description | Broflanilide is a potential insecticide and metabolized to desmethyl-broflanilide, which is a potent antagonist at the insect resistant-to-dieldrin (RDL) GABA receptor, and inhibits S. litura RDL GABAR, with an IC50 value of 1.3 nM. |
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| Related Catalog | |
| In Vitro | Broflanilide is an insecticide and metabolized to desmethyl-broflanilide, which is a potent and selective antagonist at the insect resistant-to-dieldrin (RDL) GABA receptor, and inhibits S. litura RDL GABAR, with an IC50 value of 1.3 nM. Desmethyl-broflanilide shows weak activity against human GABAA α1β2γ2 receptor, the mammalian GABAA α1β3γ2 receptor and human glycine receptor (GlyR) α1β with IC50s of >3 μM, and less potently inhibits GlyR α1-A288Gβ and GlyR α1-A288G (IC50s, 0.706, 0.149 μM)[1]. |
| References |
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 467.9±45.0 °C at 760 mmHg |
| Molecular Formula | C25H14BrF11N2O2 |
| Molecular Weight | 663.277 |
| Flash Point | 236.8±28.7 °C |
| Exact Mass | 662.006287 |
| LogP | 5.30 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.538 |
| 3-[Benzoyl(methyl)amino]-N-[2-bromo-4-(1,1,1,2,3,3,3-heptafluoro-2-propanyl)-6-(trifluoromethyl)phenyl]-2-fluorobenzamide |
| 6′-Bromo-α,α,α,2-tetrafluoro-3-(N-methylbenzamido)-4′-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]benz-o-toluidide |
| FXFFXFXFFFR CE EXFFF DMVR BF CN1&VR |
| broflanilide |
| 3-(Benzoylmethylamino)-N-[2-bromo-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]-6-(trifluoromethyl)phenyl]-2-fluorobenzamide |
| Benzamide, 3-(benzoylmethylamino)-N-[2-bromo-4-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]-6-(trifluoromethyl)phenyl]-2-fluoro- |