Anastrozole EP Impurity E

Modify Date: 2025-09-13 03:01:04

Anastrozole EP Impurity E Structure
Anastrozole EP Impurity E structure
Common Name Anastrozole EP Impurity E
CAS Number 120511-88-8 Molecular Weight 242.31600
Density 1.084 Boiling Point 382.3ºC at 760 mmHg
Molecular Formula C15H18N2O Melting Point 150-160ºC
MSDS N/A Flash Point 185ºC

 Names

Name 2,2'-[5-(Hydroxymethyl)-1,3-phenylene]bis(2-methylpropanenitrile)
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.084
Boiling Point 382.3ºC at 760 mmHg
Melting Point 150-160ºC
Molecular Formula C15H18N2O
Molecular Weight 242.31600
Flash Point 185ºC
Exact Mass 242.14200
PSA 67.81000
LogP 2.78126
InChIKey PLEAQICJSGOGID-UHFFFAOYSA-N
SMILES CC(C)(C#N)c1cc(CO)cc(C(C)(C)C#N)c1

 Synthetic Route

~96%

Anastrozole EP Impurity E Structure

Anastrozole EP ...

CAS#:120511-88-8

Literature: Jackson, Toby; Woo, L. W. Lawrence; Trusselle, Melanie N.; Chander, Surinder K.; Purohit, Atul; Reed, Michael J.; Potter, Barry V. L. Organic and Biomolecular Chemistry, 2007 , vol. 5, # 18 p. 2940 - 2952

 Synonyms

2-[3-bromomethyl-5-(cyano-dimethyl-methyl)-phenyl]-2-methyl-propionitrile
Methylpropiononitrile)
2,2'-(5-bromomethyl-1,3-phenylene)di(2-methylpropiononitrile)
forAnastrozole
5-BROMOMETHYLTETRAMETHYL-1,3-BENZENEDIACETONITRILE
2,2'-(5-hydroxymethyl-1,3-phenylene)di(2-methylpropiononitrile)
5-BROMOMETHYL-A,A,A',A'-TETRAMETHYL-1,3-BENZENEDIACETONITRILE
[2,2'-(5-bromomethyl)-1,3-phenylene]di(2-methylpropio-nitrile)
2-[3-bromomethyl 5-(cyanodimethyl-methyl)-phenyl]-methyl propionitrile
5-BROMOMETHYL-A,A,A',A'-TETRAMETHYL-1,3-BENZENEDIACETONITRIL
3,5-Bis(1-cyano-1-methylethyl)bromomethylbenezene
2-[3-(cyano-dimethyl-methyl)-5-hydroxymethyl-phenyl]-2-methyl-propionitrile
Anastrozole Impurity 10
Anastrozole EP Impurity E
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