120511-88-8
120511-88-8 structure
- Name: Anastrozole EP Impurity E
- Chemical Name: 2,2'-[5-(Hydroxymethyl)-1,3-phenylene]bis(2-methylpropanenitrile)
- CAS Number: 120511-88-8
- Molecular Formula: C15H18N2O
- Molecular Weight: 242.31600
- Create Date: 2018-12-09 16:03:38
- Modify Date: 2024-01-11 18:31:18
| Name | 2,2'-[5-(Hydroxymethyl)-1,3-phenylene]bis(2-methylpropanenitrile) |
|---|---|
| Synonyms |
2-[3-bromomethyl-5-(cyano-dimethyl-methyl)-phenyl]-2-methyl-propionitrile
Methylpropiononitrile) 2,2'-(5-bromomethyl-1,3-phenylene)di(2-methylpropiononitrile) forAnastrozole 5-BROMOMETHYLTETRAMETHYL-1,3-BENZENEDIACETONITRILE 2,2'-(5-hydroxymethyl-1,3-phenylene)di(2-methylpropiononitrile) 5-BROMOMETHYL-A,A,A',A'-TETRAMETHYL-1,3-BENZENEDIACETONITRILE [2,2'-(5-bromomethyl)-1,3-phenylene]di(2-methylpropio-nitrile) 2-[3-bromomethyl 5-(cyanodimethyl-methyl)-phenyl]-methyl propionitrile 5-BROMOMETHYL-A,A,A',A'-TETRAMETHYL-1,3-BENZENEDIACETONITRIL 3,5-Bis(1-cyano-1-methylethyl)bromomethylbenezene 2-[3-(cyano-dimethyl-methyl)-5-hydroxymethyl-phenyl]-2-methyl-propionitrile Anastrozole Impurity 10 Anastrozole EP Impurity E |
| Density | 1.084 |
|---|---|
| Boiling Point | 382.3ºC at 760 mmHg |
| Melting Point | 150-160ºC |
| Molecular Formula | C15H18N2O |
| Molecular Weight | 242.31600 |
| Flash Point | 185ºC |
| Exact Mass | 242.14200 |
| PSA | 67.81000 |
| LogP | 2.78126 |
|
~96%
120511-88-8 |
| Literature: Jackson, Toby; Woo, L. W. Lawrence; Trusselle, Melanie N.; Chander, Surinder K.; Purohit, Atul; Reed, Michael J.; Potter, Barry V. L. Organic and Biomolecular Chemistry, 2007 , vol. 5, # 18 p. 2940 - 2952 |
| Precursor 1 | |
|---|---|
| DownStream 3 | |
![2-[3-(chloromethyl)-5-(2-cyanopropan-2-yl)phenyl]-2-methylpropanenitrile structure](https://image.chemsrc.com/caspic/281/120511-91-3.png)