Atabecestat

Modify Date: 2023-02-01 21:27:35

Atabecestat Structure
Atabecestat structure
Common Name Atabecestat
CAS Number 1200493-78-2 Molecular Weight 367.400
Density 1.4±0.1 g/cm3 Boiling Point N/A
Molecular Formula C18H14FN5OS Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Atabecestat


Atabecestat (JNJ-54861911, JNJ54861911) is a novel potent, oral beta-secretase (BACE) inhibitor for treatment of Alzheimer's Disease.

 Names

Name atabecestat
Synonym More Synonyms

 Atabecestat Biological Activity

Description Atabecestat (JNJ-54861911, JNJ54861911) is a novel potent, oral beta-secretase (BACE) inhibitor for treatment of Alzheimer's Disease.
Related Catalog
Target

IC50: BACE1[1]

References

[1]. Timmers M, et al. Profiling the dynamics of CSF and plasma Aβ reduction after treatment with JNJ-54861911, a potent oral BACE inhibitor.Alzheimers Dement (N Y). 2016 Aug 24;2(3):202-212.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Molecular Formula C18H14FN5OS
Molecular Weight 367.400
Exact Mass 367.090302
LogP 1.63
Index of Refraction 1.681

 Synonyms

JNJ-54861911
N-{3-[(4S)-2-Amino-4-methyl-4H-1,3-thiazin-4-yl]-4-fluorophenyl}-5-cyano-2-pyridinecarboxamide
2-Pyridinecarboxamide, N-[3-[(4S)-2-amino-4-methyl-4H-1,3-thiazin-4-yl]-4-fluorophenyl]-5-cyano-
atabecestat
Top Suppliers:I want be here
  • DC Chemicals Limited
  • China
  • Product Name: Atabecestat
  • Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
  • Purity: 98.0%
  • Stocking Period: 3 Day
  • Contact: Tony Cao

Get all suppliers and price by the below link:

Atabecestat suppliers

Atabecestat price

Hot Compounds More...
Dichloromethane
CAS#:75-09-2
Polyacrylic acid
CAS#:9003-01-4
sodium carbonate
CAS#:497-19-8
Silicon dioxide
CAS#:7631-86-9
Triethanolamine
CAS#:102-71-6
Demeton
CAS#:126-75-0
Water
CAS#:7732-18-5
4-(4-Piperidinyl)morpholine dihydrochloride
CAS#:53617-35-9
Diclofenac sodium
CAS#:15307-79-6
Budesonide
CAS#:51372-29-3