Dexloxiglumide

Modify Date: 2025-08-25 18:07:21

Dexloxiglumide structure	Common Name	Dexloxiglumide
	CAS Number	119817-90-2	Molecular Weight	461.37900
	Density	1.233g/cm3	Boiling Point	632.2ºC at 760mmHg
	Molecular Formula	C₂₁H₃₀Cl₂N₂O₅	Melting Point	N/A
	MSDS	N/A	Flash Point	336.1ºC

Use of Dexloxiglumide

Dexloxiglumide is a selective cholecystokinin type A (CCKA) receptor antagonist[1]. Dexloxiglumide, the active enantiomer of Loxiglumide, inhibits smooth muscle cell contractions induced by cholecystokinin-octapeptide (CCK-8)[2].

Name	(4R)-4-[(3,4-dichlorobenzoyl)amino]-5-[3-methoxypropyl(pentyl)amino]-5-oxopentanoic acid
Synonym	More Synonyms

Description	Dexloxiglumide is a selective cholecystokinin type A (CCKA) receptor antagonist[1]. Dexloxiglumide, the active enantiomer of Loxiglumide, inhibits smooth muscle cell contractions induced by cholecystokinin-octapeptide (CCK-8)[2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Cholecystokinin Receptor Research Areas >> Metabolic Disease
References	[1]. Scarpignato C, et al. Effect of dexloxiglumide and spiroglumide, two new CCK-receptor antagonists, on gastric emptying and secretion in the rat: evaluation of their receptor selectivity in vivo. Aliment Pharmacol Ther. 1996 Jun;10(3):411-9. [2]. Maselli MA, et al. CCK1 receptor antagonist, dexloxiglumide: effects on human isolated gallbladder. Potential clinical applications. Minerva Gastroenterol Dietol. 2003 Sep;49(3):211-6.

Description

Related Catalog

Signaling Pathways >> GPCR/G Protein >> Cholecystokinin Receptor

Research Areas >> Metabolic Disease

References

[1]. Scarpignato C, et al. Effect of dexloxiglumide and spiroglumide, two new CCK-receptor antagonists, on gastric emptying and secretion in the rat: evaluation of their receptor selectivity in vivo. Aliment Pharmacol Ther. 1996 Jun;10(3):411-9.

[2]. Maselli MA, et al. CCK1 receptor antagonist, dexloxiglumide: effects on human isolated gallbladder. Potential clinical applications. Minerva Gastroenterol Dietol. 2003 Sep;49(3):211-6.

Density	1.233g/cm3
Boiling Point	632.2ºC at 760mmHg
Molecular Formula	C₂₁H₃₀Cl₂N₂O₅
Molecular Weight	461.37900
Flash Point	336.1ºC
Exact Mass	460.15300
PSA	95.94000
LogP	4.40280
Vapour Pressure	7.51E-17mmHg at 25°C
Index of Refraction	1.537
InChIKey	QNQZBKQEIFTHFZ-GOSISDBHSA-N
SMILES	CCCCCN(CCCOC)C(=O)C(CCC(=O)O)NC(=O)c1ccc(Cl)c(Cl)c1

Hazard Codes	Xn,Xi

CR-2017

Dexloxiglumida [INN-Spanish]

Dexloxiglumidum [INN-Latin]

Dexloxiglumidum

Dexloxiglumida

Dexloxiglumide

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Dexloxiglumide
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Dexloxiglumide
Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
Purity: 98.0%
Delivery: 10 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: DEXLOXIGLUMIDE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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