1-amino-2-naphthol hydrochloride

Modify Date: 2025-08-23 13:03:00

1-amino-2-naphthol hydrochloride Structure
1-amino-2-naphthol hydrochloride structure
Common Name 1-amino-2-naphthol hydrochloride
CAS Number 1198-27-2 Molecular Weight 195.64500
Density N/A Boiling Point 336.8ºC at 760mmHg
Molecular Formula C10H10ClNO Melting Point 250 °C (dec.)(lit.)
MSDS Chinese USA Flash Point 157.5ºC
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Warning

 Names

Name 1-Amino-2-naphthol hydrochloride
Synonym More Synonyms

 Chemical & Physical Properties

Boiling Point 336.8ºC at 760mmHg
Melting Point 250 °C (dec.)(lit.)
Molecular Formula C10H10ClNO
Molecular Weight 195.64500
Flash Point 157.5ºC
Exact Mass 195.04500
PSA 46.25000
LogP 3.51080
Vapour Pressure 5.61E-05mmHg at 25°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QL3335000
CHEMICAL NAME :
2-Naphthol, 1-amino-, hydrochloride
CAS REGISTRY NUMBER :
1198-27-2
LAST UPDATED :
199701
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C10-H9-N-O.Cl-H
MOLECULAR WEIGHT :
195.66
WISWESSER LINE NOTATION :
L66J BZ CQ &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Implant
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - tumors

MUTATION DATA

TYPE OF TEST :
DNA repair
TEST SYSTEM :
Bacteria - Escherichia coli
DOSE/DURATION :
500 ug/well/16H
REFERENCE :
CBINA8 Chemico-Biological Interactions. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1969- Volume(issue)/page/year: 15,219,1976

 Safety Information

Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Warning
Hazard Statements H302 + H312 + H332-H315-H319-H335-H351
Precautionary Statements P261-P280-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn:Harmful;
Risk Phrases R20/21/22;R36/37/38;R40
Safety Phrases S26-S27-S36/37/39
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS QL3335000
HS Code 2922299090

 Synthetic Route

~89%

1-amino-2-naphthol hydrochloride Structure

1-amino-2-napht...

CAS#:1198-27-2

Literature: Monatshefte fur Chemie, , vol. 138, # 8 p. 755 - 757

~91%

1-amino-2-naphthol hydrochloride Structure

1-amino-2-napht...

CAS#:1198-27-2

Literature: Monatshefte fur Chemie, , vol. 138, # 8 p. 755 - 757

~%

1-amino-2-naphthol hydrochloride Structure

1-amino-2-napht...

CAS#:1198-27-2

Literature: Medicinal Chemistry Research, , vol. 22, # 4 p. 1604 - 1617

 Customs

HS Code 2922299090
Summary 2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Articles8

More Articles
Anaerobic metabolism of 1-amino-2-naphthol-based azo dyes (Sudan dyes) by human intestinal microflora.

Appl. Environ. Microbiol. 73(23) , 7759-62, (2007)

The rates of metabolism of Sudan I and II and Para Red by human intestinal microflora were high compared to those of Sudan III and IV under anaerobic conditions. Metabolites of the dyes were identifie...

Evaluation of impact of exposure of Sudan azo dyes and their metabolites on human intestinal bacteria.

Anaerobe 18(4) , 445-53, (2012)

Sudan azo dyes are banned for food usage in most countries, but they are illegally used to maintain or enhance the color of food products due to low cost, bright staining, and wide availability of the...

Effects of Orange II and Sudan III azo dyes and their metabolites on Staphylococcus aureus.

J. Ind. Microbiol. Biotechnol. 38(10) , 1729-38, (2011)

Azo dyes are widely used in the plastic, paper, cosmetics, food, and pharmaceutical industries. Some metabolites of these dyes are potentially genotoxic. The toxic effects of azo dyes and their potent...

 Synonyms

1-Amino-2-naphthol Hydrochloride
EINECS 214-830-8
1-Amino-2-naphtholhydrochloride
MFCD00012561
1-Aminonaphthalen-2-ol hydrochloride
1-aminonaphthalen-2-ol,hydrochloride
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