BMS 814580 phosphate
Modify Date: 2024-01-15 20:00:19
BMS 814580 phosphate structure
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Common Name | BMS 814580 phosphate | ||
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| CAS Number | 1197420-12-4 | Molecular Weight | 584.912 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H20ClF2N2O7PS | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BMS 814580 phosphateA highly potent, subtype-selective melanin concentrating hormone receptor 1 (MCHR1) inhibitor with Ki of 17 nM, without inhibitory activity for MCHR2 at 10 uM; exhibits functional potency with Kb of 117 nM in FLIPR-based assay, with no activity for MCHR2 at 10 uM, dose-dependently reduces body weight in chronic diet-induced obese models with excellent safety profile. |
| Name | BMS 814580 phosphate |
|---|
| Description | A highly potent, subtype-selective melanin concentrating hormone receptor 1 (MCHR1) inhibitor with Ki of 17 nM, without inhibitory activity for MCHR2 at 10 uM; exhibits functional potency with Kb of 117 nM in FLIPR-based assay, with no activity for MCHR2 at 10 uM, dose-dependently reduces body weight in chronic diet-induced obese models with excellent safety profile. |
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| References | References 1. Ahmad S, et al. J Med Chem. 2016 Oct 13;59(19):8848-8858. View Related Products by Target Melanin-concentrating Hormone Receptor (MCHR) |
| Molecular Formula | C24H20ClF2N2O7PS |
|---|---|
| Molecular Weight | 584.912 |