5-Chloro-2',3'-dideoxy-3'-fluoro-uridine

Modify Date: 2024-01-12 10:21:34

5-Chloro-2',3'-dideoxy-3'-fluoro-uridine structure	Common Name	5-Chloro-2',3'-dideoxy-3'-fluoro-uridine
	CAS Number	119644-22-3	Molecular Weight	264.64
	Density	1.6±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₉H₁₀ClFN₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 5-Chloro-2',3'-dideoxy-3'-fluoro-uridine

Raluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	5-chloro-1-[(2R,4S,5R)-4-fluoro-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
Synonym	More Synonyms

Description	Raluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.