119644-22-3

119644-22-3 structure
119644-22-3 structure
  • Name: 5-Chloro-2',3'-dideoxy-3'-fluoro-uridine
  • Chemical Name: 5-chloro-1-[(2R,4S,5R)-4-fluoro-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
  • CAS Number: 119644-22-3
  • Molecular Formula: C9H10ClFN2O4
  • Molecular Weight: 264.64
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
  • Create Date: 2019-01-01 19:26:07
  • Modify Date: 2024-01-12 10:21:34
  • Raluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name 5-chloro-1-[(2R,4S,5R)-4-fluoro-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
Synonyms Raluridine
Fddclurd
FddClU
Uridine, 5-chloro-2',3'-dideoxy-3'-fluoro-
935U83
FddCIU
5-Chloro-2',3'-dideoxy-3'-fluorouridine
BW 935U83
2',3'-Dideoxy-3'-fluoro-5-chlorouridine
5-CHLORO-2',3'-DIDEOXY-3'-FLUORO-URIDINE
Description Raluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Density 1.6±0.1 g/cm3
Molecular Formula C9H10ClFN2O4
Molecular Weight 264.64
Exact Mass 264.031311
PSA 84.32000
LogP -0.75
Index of Refraction 1.588