(R)-N-METHYL-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHYLAMINE

Modify Date: 2024-01-14 23:45:52

(R)-N-METHYL-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHYLAMINE Structure
(R)-N-METHYL-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHYLAMINE structure
Common Name (R)-N-METHYL-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHYLAMINE
CAS Number 119618-21-2 Molecular Weight 393.94700
Density N/A Boiling Point N/A
Molecular Formula C22H32ClNO3 Melting Point 52-54ºC
MSDS N/A Flash Point N/A

 Use of (R)-N-METHYL-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]ETHYLAMINE


(R)-Oxybutynin (Aroxybutynin), a (R)-isomer of Oxybutynin, is an orally active muscarinic receptor antagonist. (R)-Oxybutynin has antimuscarinic, antispasmodic and anticholinergic activity, competitively antagonizes Carbachol-induced contractions. (R)-Oxybutynin can be used for researching incontinence due to neurogenic bladder dysfunction[1][2][3].

 Names

Name (r)-oxybutynin chloride
Synonym More Synonyms

  Biological Activity

Description (R)-Oxybutynin (Aroxybutynin), a (R)-isomer of Oxybutynin, is an orally active muscarinic receptor antagonist. (R)-Oxybutynin has antimuscarinic, antispasmodic and anticholinergic activity, competitively antagonizes Carbachol-induced contractions. (R)-Oxybutynin can be used for researching incontinence due to neurogenic bladder dysfunction[1][2][3].
Related Catalog
Target

Muscarinic receptor, mAChR[1][2]

References

[1]. Smith ER, et al. Comparison of the antimuscarinic and antispasmodic actions of racemic oxybutynin and desethyloxybutynin and their enantiomers with those of racemic terodiline. Arzneimittelforschung. 1998 Oct;48(10):1012-8.

[2]. Siddiqui MA, et al. Oxybutynin extended-release: a review of its use in the management of overactive bladder. Drugs. 2004;64(8):885-912.

[3]. Zobrist RH, et al. Pharmacokinetics of the R- and S-enantiomers of oxybutynin and N-desethyloxybutynin following oral and transdermal administration of the racemate in healthy volunteers. Pharm Res. 2001 Jul;18(7):1029-34.

 Chemical & Physical Properties

Melting Point 52-54ºC
Molecular Formula C22H32ClNO3
Molecular Weight 393.94700
Exact Mass 393.20700
PSA 49.77000
LogP 4.14490

 Synonyms

Benzeneacetic acid,a-cyclohexyl-a-hydroxy-,4-(diethylamino)-2-butynyl ester,(aR)-(9CI)
(R)-A-PHENYLCYCLOHEXANEGLYCOLIC ACID 4-(DIETHYLAMINO)-2-BUTYNYL ESTER,HYDROCHLORIDE
[3H]-Oxybutynin
(R)-OXYBUTYNIN HCL
(R)-Oxybutynin
Benzeneacetic acid,a-cyclohexyl-a-hydroxy-,4-(diethylamino)-2-butynyl ester,(R)
(R)-Oxybutynin hydrochloride
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