Loureirin A

Modify Date: 2024-01-02 13:13:31

Loureirin A structure	Common Name	Loureirin A
	CAS Number	119425-89-7	Molecular Weight	286.322
	Density	1.2±0.1 g/cm3	Boiling Point	479.1±40.0 °C at 760 mmHg
	Molecular Formula	C₁₇H₁₈O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	175.8±20.8 °C

Use of Loureirin A

Loureirin A is a flavonoid extracted from Dragon's Blood, can inhibit Akt phosphorylation, and has antiplatelet activity.

Name	Loureirin A
Synonym	More Synonyms

Description	Loureirin A is a flavonoid extracted from Dragon's Blood, can inhibit Akt phosphorylation, and has antiplatelet activity.
Related Catalog	Natural Products >> Flavonoids Research Areas >> Cardiovascular Disease
Target	Akt
In Vitro	Loureirin A (50 μM, 100 μM) inhibits collagen-induced platelet ATP secretion and thrombin-stimulated P-selectin expression in a dose-dependent manner. Loureirin A also significantly impairs platelet spreading on immobilized fibrinogen. Loureirin A almost completely eliminates collagen-induced Akt phosphorylation at Ser473 at the dose of 100 μM, and has an additive inhibitory effect with the phosphoinositide 3-kinase (PI3K) inhibitor Ly294002 on collage-induced Akt phosphorylation in platelets at 50 μM[1].
References	[1]. Hao HZ, et al. Antiplatelet activity of loureirin A by attenuating Akt phosphorylation: In vitro studies. Eur J Pharmacol. 2015 Jan 5;746:63-9.

Density	1.2±0.1 g/cm3
Boiling Point	479.1±40.0 °C at 760 mmHg
Molecular Formula	C₁₇H₁₈O₄
Molecular Weight	286.322
Flash Point	175.8±20.8 °C
Exact Mass	286.120514
PSA	55.76000
LogP	3.30
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.573
Storage condition	2-8C

3-(2,4-Dimethoxyphenyl)-1-(4-hydroxyphenyl)propan-1-one

3-(2,4-Dimethoxyphenyl)-1-(4-hydroxyphenyl)-1-propanone

1-Propanone, 3-(2,4-dimethoxyphenyl)-1-(4-hydroxyphenyl)-

BioBioPha
China
Product Name: Loureirin A
Price: ￥Inquiry/20mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Xueping-Zheng

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Loureirin A
Price: ￥1788.0/20mg
Purity: 98.0%
Stocking Period: 1 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Loureirin A
Price: $280.0/20mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Loureirin A
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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Price: $198/10mM*1mLinDMSO

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