Thiabendazole-d4

Modify Date: 2024-01-08 19:00:48

Thiabendazole-d4 Structure
Thiabendazole-d4 structure
Common Name Thiabendazole-d4
CAS Number 1190007-20-5 Molecular Weight 205.272
Density 1.4±0.1 g/cm3 Boiling Point 446.0±37.0 °C at 760 mmHg
Molecular Formula C10H3D4N3S Melting Point N/A
MSDS N/A Flash Point 226.2±16.9 °C

 Use of Thiabendazole-d4


Thiabendazole-d4 is the deuterium labeled EIDD-1931. EIDD-1931 (Beta-d-N4-hydroxycytidine; NHC) is a novel nucleoside analog and behaves as a potent anti-virus agent. EIDD-1931 effectively inhibits the replication activity of venezuelan equine encephaliti

 Names

Name 2-(1,3-Thiazol-4-yl)(4,5,6,7-2H4)-1H-benzimidazole
Synonym More Synonyms

 Thiabendazole-d4 Biological Activity

Description Thiabendazole-d4 is the deuterium labeled EIDD-1931. EIDD-1931 (Beta-d-N4-hydroxycytidine; NHC) is a novel nucleoside analog and behaves as a potent anti-virus agent. EIDD-1931 effectively inhibits the replication activity of venezuelan equine encephaliti
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 446.0±37.0 °C at 760 mmHg
Molecular Formula C10H3D4N3S
Molecular Weight 205.272
Flash Point 226.2±16.9 °C
Exact Mass 205.061172
LogP 2.47
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.740
Storage condition -20°C

 Synonyms

2-(1,3-Thiazol-4-yl)(4,5,6,7-2H4)-1H-benzimidazole
1H-Benzimidazole-4,5,6,7-d4, 2-(4-thiazolyl)-
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