(±)-Darifenacin-d4

Modify Date: 2024-01-09 15:51:23

(±)-Darifenacin-d4 structure	Common Name	(±)-Darifenacin-d4
	CAS Number	1189701-43-6	Molecular Weight	430.57
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₈H₂₆D₄N₂O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (±)-Darifenacin-d4

(±)-Darifenacin-d4 is deuterium labeled (±)-Darifenacin. (±)-Darifenacin is the racemate of Darifenacin. Darifenacin is a selective M3 muscarinic receptor antagonist[1].

Name	rac Darifenacin-d4
Synonym	More Synonyms

Description	(±)-Darifenacin-d4 is deuterium labeled (±)-Darifenacin. (±)-Darifenacin is the racemate of Darifenacin. Darifenacin is a selective M3 muscarinic receptor antagonist[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Neuronal Signaling >> mAChR Signaling Pathways >> GPCR/G Protein >> mAChR Research Areas >> Neurological Disease
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Hegde SS, et al. Functional role of M2 and M3 muscarinic receptors in the urinary bladder of rats in vitro and in vivo. Br J Pharmacol, 1997, 120(8), 1409-1418.

Molecular Formula	C₂₈H₂₆D₄N₂O₂
Molecular Weight	430.57
Exact Mass	430.25600
PSA	56.55000
LogP	5.04510

2,2-diphenyl-2-[1-[1,1,2,2-tetradeuterio-2-(2,3-dihydro-1-benzofuran-5-yl)ethyl]pyrrolidin-3-yl]acetamide

(±)-Darifenacin-d4

Use of (±)-Darifenacin-d4

Names

(±)-Darifenacin-d4 Biological Activity

Chemical & Physical Properties

Synonyms