ularitide

Modify Date: 2024-01-11 16:48:33

ularitide Structure
ularitide structure
Common Name ularitide
CAS Number 118812-69-4 Molecular Weight 3505.927
Density 1.6±0.1 g/cm3 Boiling Point N/A
Molecular Formula C145H234N52O44S3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ularitide


Ularitide (Urodilatin), natriuretic peptide, is a vasodilator. Ularitide binds to and activates renal receptors. Ularitide also regulates renal dopamine metabolism Ularitide can be used in the research of heart failure[1][2][4][5].

 Names

Name ularitide
Synonym More Synonyms

 ularitide Biological Activity

Description Ularitide (Urodilatin), natriuretic peptide, is a vasodilator. Ularitide binds to and activates renal receptors. Ularitide also regulates renal dopamine metabolism Ularitide can be used in the research of heart failure[1][2][4][5].
Related Catalog
In Vitro Ularitide increases the amount of cyclic nucleotides and decreases the raise in permeability in HUVEC cells[2]. Ularitide (1 nM-1 μM, 15 min) reverses methacholine-evoked contraction in bovine bronchi[3]. Ularitide (1 μM, 0-300 s) increases cyclic GMP levels in the presence of phosphoramidon in bovine bronchi[3].
In Vivo Ularitide (10 nmol/kg, s.c., once) increases in urine volume and sodium excretion in arteriovenous (AV) fistula dogs[1]. Animal Model: Female dogs with or without surgically induced chronic aortocaval fistula[1] Dosage: 5 and 10 pmol/kg/min Administration: i.v. infusions for for 75 min, and thereafter at 10 pmol/kg/min for another 75 min. Result: Increased in urine volume and sodium excretion with high-output CHF.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Molecular Formula C145H234N52O44S3
Molecular Weight 3505.927
Exact Mass 3503.683350
LogP -16.35
Index of Refraction 1.692

 Synonyms

ularitide
Urodilatin (human)
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