N-(4-((3-(2,4-diamino-1,6-dihydro-6-oxo-5-pyrimidinyl)propyl)amino)benzoyl)glutamic acid
Modify Date: 2024-04-11 13:32:03
N-(4-((3-(2,4-diamino-1,6-dihydro-6-oxo-5-pyrimidinyl)propyl)amino)benzoyl)glutamic acid structure
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Common Name | N-(4-((3-(2,4-diamino-1,6-dihydro-6-oxo-5-pyrimidinyl)propyl)amino)benzoyl)glutamic acid | ||
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| CAS Number | 118252-44-1 | Molecular Weight | 432.43000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H24N6O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of N-(4-((3-(2,4-diamino-1,6-dihydro-6-oxo-5-pyrimidinyl)propyl)amino)benzoyl)glutamic acid5-DACTHF (543U76) is an inhibitor of purine de novo biosynthesis. 5-DACTHF is a GAR-TFase and AICAR-TFase inhibitor (IC50: 3 and 94 μM). 5-DACTHF is a potent antitumor agent[1]. |
| Name | (2S)-2-[[4-[3-(2,6-diamino-4-oxo-1H-pyrimidin-5-yl)propylamino]benzoyl]amino]pentanedioic acid |
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| Synonym | More Synonyms |
| Description | 5-DACTHF (543U76) is an inhibitor of purine de novo biosynthesis. 5-DACTHF is a GAR-TFase and AICAR-TFase inhibitor (IC50: 3 and 94 μM). 5-DACTHF is a potent antitumor agent[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C19H24N6O6 |
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| Molecular Weight | 432.43000 |
| Exact Mass | 432.17600 |
| PSA | 214.51000 |
| LogP | 1.41430 |
| 5-Deazacyclotetrahydrofolate |
| n-(4-{[3-(2,6-diamino-4-oxo-1,4-dihydropyrimidin-5-yl)propyl]amino}benzoyl)-l-glutamic acid |
| 543U76 |
| 5-DACTHF |