RU-302
Modify Date: 2025-09-21 09:22:11
RU-302 structure
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Common Name | RU-302 | ||
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| CAS Number | 1182129-77-6 | Molecular Weight | 475.53 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H24F3N3O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of RU-302RU-302 is a pan TAM inhibitor that blocks the interface between the TAM Ig1 ectodomain and the Gas6 Lg domain. RU-302 effectively blocks Gas6-inducible Axl receptor activation with a low micromolar IC50in cell assays, and suppresses lung cancer tumor growth[1]. |
| Name | RU-302 |
|---|
| Description | RU-302 is a pan TAM inhibitor that blocks the interface between the TAM Ig1 ectodomain and the Gas6 Lg domain. RU-302 effectively blocks Gas6-inducible Axl receptor activation with a low micromolar IC50in cell assays, and suppresses lung cancer tumor growth[1]. |
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| Related Catalog | |
| Target |
TAM, Axl[1] |
| References |
| Molecular Formula | C24H24F3N3O2S |
|---|---|
| Molecular Weight | 475.53 |
| InChIKey | IZHRNXCFYZERFF-UHFFFAOYSA-N |
| SMILES | Cc1noc(C)c1CSc1ccccc1C(=O)N1CCN(c2cccc(C(F)(F)F)c2)CC1 |
| Hazard Codes | Xi |
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