CLP-290
Modify Date: 2025-08-25 18:58:54
CLP-290 structure
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Common Name | CLP-290 | ||
|---|---|---|---|---|
| CAS Number | 1181083-81-7 | Molecular Weight | 404.458 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 553.7±60.0 °C at 760 mmHg | |
| Molecular Formula | C19H21FN4O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 288.6±32.9 °C | |
Use of CLP-290CLP290 is an orally available activator of the neuron-specific K+-Cl− cotransporter KCC2, displays potential for treatment of a wide range of neurological and psychiatric indications. CLP290 can significantly lower blood arginine-vasopressin (AVP) and glucose levels in STZ rats[1][2]. |
| Name | 5-Fluoro-2-{(Z)-[4-oxo-2-(tetrahydro-1(2H)-pyridazinyl)-1,3-thiazol-5(4H)-ylidene]methyl}phenyl 1-pyrrolidinecarboxylate |
|---|---|
| Synonym | More Synonyms |
| Description | CLP290 is an orally available activator of the neuron-specific K+-Cl− cotransporter KCC2, displays potential for treatment of a wide range of neurological and psychiatric indications. CLP290 can significantly lower blood arginine-vasopressin (AVP) and glucose levels in STZ rats[1][2]. |
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| Related Catalog | |
| Target |
KCC2[1] |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 553.7±60.0 °C at 760 mmHg |
| Molecular Formula | C19H21FN4O3S |
| Molecular Weight | 404.458 |
| Flash Point | 288.6±32.9 °C |
| Exact Mass | 404.131836 |
| LogP | 2.89 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.691 |
| MFCD28166314 |
| 1-Pyrrolidinecarboxylic acid, 5-fluoro-2-[(Z)-[4-oxo-2-(tetrahydro-1(2H)-pyridazinyl)-5(4H)-thiazolylidene]methyl]phenyl ester |
| 5-Fluoro-2-{(Z)-[4-oxo-2-(tetrahydro-1(2H)-pyridazinyl)-1,3-thiazol-5(4H)-ylidene]methyl}phenyl 1-pyrrolidinecarboxylate |