L-LYSYL-D-PROLYL-L-THREONINE
Modify Date: 2025-09-19 08:06:08
L-LYSYL-D-PROLYL-L-THREONINE structure
|
Common Name | L-LYSYL-D-PROLYL-L-THREONINE | ||
|---|---|---|---|---|
| CAS Number | 117027-34-6 | Molecular Weight | 344.41 | |
| Density | 1.288g/cm3 | Boiling Point | 691.3ºC at 760mmHg | |
| Molecular Formula | C15H28N4O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 371.9ºC | |
Use of L-LYSYL-D-PROLYL-L-THREONINELys-D-Pro-Thr, an IL-1beta analogue, is a potent IL-1 inhibitor. Lys-D-Pro-Thr inhibits the protective effects of IL-1 beta[1][2]. |
| Name | h-lys-d-pro-thr-oh |
|---|---|
| Synonym | More Synonyms |
| Description | Lys-D-Pro-Thr, an IL-1beta analogue, is a potent IL-1 inhibitor. Lys-D-Pro-Thr inhibits the protective effects of IL-1 beta[1][2]. |
|---|---|
| Related Catalog | |
| Target |
IL-1 |
| In Vivo | Lys-D-Pro-Thr (10 mg/kg; 腹腔给药; 持续 4 天) 抑制 fMLP (HY-P0224) 和 MMK-1 (HY-P1117) 对依托泊苷 (HY-13629) 诱导脱发的保护作用[1]。 Animal Model: 11-d-old rats[1] Dosage: 10 mg/kg Administration: IP; for 4 days Result: Inhibited the protective effect of fMLP and that of MMK-1 against Etoposide-induced alopecia. It alone did not induce alopecia. |
| References |
| Density | 1.288g/cm3 |
|---|---|
| Boiling Point | 691.3ºC at 760mmHg |
| Molecular Formula | C15H28N4O5 |
| Molecular Weight | 344.41 |
| Flash Point | 371.9ºC |
| Exact Mass | 344.20600 |
| PSA | 158.98000 |
| LogP | 0.11330 |
| Vapour Pressure | 4.12E-22mmHg at 25°C |
| Index of Refraction | 1.56 |
| Safety Phrases | 22-24/25 |
|---|
| l-lysyl-d-prolyl-l-threonine |
| l-lys-d-pro-l-thr |
| lys-d-pro-thr |
| interleukin 1b antagonist |
| [D-Pro194]-IL-1 b (193-195) (human) |