(Tyr0)-Neurokinin A

Modify Date: 2024-01-08 18:22:17

(Tyr0)-Neurokinin A Structure
(Tyr0)-Neurokinin A structure
Common Name (Tyr0)-Neurokinin A
CAS Number 116868-93-0 Molecular Weight 1296.494
Density 1.4±0.1 g/cm3 Boiling Point 1399.4±75.0 °C at 760 mmHg
Molecular Formula C59H89N15O16S Melting Point N/A
MSDS N/A Flash Point 800.1±37.1 °C

 Use of (Tyr0)-Neurokinin A


Tyr0-Neurokinin A is a neuropeptide belongs to tachykinin peptide family. Tyr0-Neurokinin A is an agonist of Tacr2. Tyr0-Neurokinin A can be used in the research of insulin resistance, obesity, diabetes[1][2].

 Names

Name [Tyr0]-Neurokinin A
Synonym More Synonyms

 (Tyr0)-Neurokinin A Biological Activity

Description Tyr0-Neurokinin A is a neuropeptide belongs to tachykinin peptide family. Tyr0-Neurokinin A is an agonist of Tacr2. Tyr0-Neurokinin A can be used in the research of insulin resistance, obesity, diabetes[1][2].
Related Catalog
Target

Tachykinin Receptor 2 (Tacr2)[2]

References

[1]. Gao X, et al. The study of the conformation and interaction of two tachykinin peptides in membrane mimicking systems by NMR spectroscopy and pulsed field gradient diffusion. Biopolymers. 1999 Oct 15;50(5):555-68.  

[2]. Gerhart-Hines Zachary, et al. Peptide agonists of Tacr2 for treatment of insulin resistance, diabetes and/or obesity. Patent. WO2021073742.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 1399.4±75.0 °C at 760 mmHg
Molecular Formula C59H89N15O16S
Molecular Weight 1296.494
Flash Point 800.1±37.1 °C
Exact Mass 1295.633301
LogP 8.61
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.650

 Synonyms

2-Thia-6,9,12,15,18,21-hexaazapentacosa-6,9,12,15,18,21-hexaen-25-oic acid, 23-[[(2S,3R)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-amino-1-hydroxy-3-(4-hydroxyphenyl)propylidene]amino]-1-hydroxy-3-(1H-imidazol-5-yl)propylidene]amino]-1-hydroxyhexylidene]amino]-1,3-dihydroxybutylidene]amino]-7,10,13,16,19,22-hexahydroxy-5-(hydroxyiminomethyl)-20-(hydroxymethyl)-14-(1-methylethyl)-8-(2-methylpropyl)-17-(phenylmethyl)-, (5S,8S,14S,17S,20S,23S)-
(5S,8S,14S,17S,20S,23S)-23-{[(2S,3R)-2-{[(2S)-6-Amino-2-{[(2S)-2-{[(2S)-2-amino-1-hydroxy-3-(4-hydroxyphenyl)propylidene]amino}-1-hydroxy-3-(1H-imidazol-5-yl)propylidene]amino}-1-hydroxyhexylidene]amino}-1,3-dihydroxybutylidene]amino}-17-benzyl-7,10,13,16,19,22-hexahydroxy-5-[hydroxy(imino)methyl]-20-(hydroxymethyl)-8-isobutyl-14-isopropyl-2-thia-6,9,12,15,18,21-hexaazapentacosa-6,9,12,15,18,21-hexaen-25-oic acid
YHKTDSFVGLM-NH2